“Minds Make Molecules – Molecules Make Sense.”
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Albert Gjedde
Curriculum Vitae
Current Positions
Emeritus Professor of Neurobiology and Pharmacology
- Department of Neuroscience, Faculty of Health & Medical Sciences, Panum Institute, University of Copenhagen, Copenhagen, Denmark.
Adjunct Professor of Neurology and Neurosurgery
- Department of Neurology, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Affiliated Principal Investigator of Neuropsychiatry
- Translational Neuropsychiatry Unit, Department of Clinical Medicine, Faculty of Health, Aarhus University Hospital, Aarhus, Denmark.
Past Positions
1973 – 1973: Resident Physician
- Department of Neurology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
1973 – 1976: Research Associate
- Department of Neurology, Department of Neurology, The New York Hospital-Cornell Medical Center, New York, NY, USA
1976 – 1976: Basic Medical Sciences Fellowship
- Institute of Biophysics, Copenhagen University, Copenhagen, Denmark
1976 – 1979: Research Associate
- Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
1979 – 1981: Assistant Professor
- Medical Physiology, University of Copenhagen, Copenhagen, Denmark
1981 – 1994: Associate Professor (tenure)
- Medical Physiology, University of Copenhagen, Copenhagen, Denmark.
1986 – 1989: Associate Professor (tenure)
- Department of Neurology, Montreal Neurological Institute, McGill University, Montreal, Québec, Canada.
1989 – 1994: Director
- McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Québec, Canada.
1989 – 1994: Professor of Neurology and Neurosurgery (tenure)
- Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada.
1994 – 2000: Danish Medical Research Council, Professor of Brain Research (tenure)
- Aarhus University, Aarhus, Denmark.
1994 – 2008: Head of Department
- PET Center, Aarhus University Hospitals, Aarhus, Denmark.
2000-2008: Professor of Medical Neurobiology (tenure)
- PET Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
2001 – 2004: Director
- Centre of Functionally Integrative Neuroscience (CFIN), DGF Foundation of Basic Research in Denmark, Aarhus University, Aarhus, Denmark.
2008 – 2014: Chair of Department
- Department of Neuroscience and Pharmacology, Faculty Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
2008 – 2018: Professor of Neurobiology and Pharmacology
- Department of Neuroscience and Pharmacology, Faculty Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Research
Albert Gjedde’s research focuses on the relations between neuroplasticity and neurotransmission revealed by mapping radioligand binding and the neuroplastic changes of brain functions.
The investigations explore the relation between energy metabolism and neurotransmission by recording the changes of energy metabolism and consciousness under pharmacological and other manipulations.
Albert Gjedde uses PET to understand 1) the synthesis of radioligand and tracer molecules that match the neurotransmitter molecules and the behavior of these transmitters under different functional conditions of the brain, normal as well as pathological, and 2) the spatial and temporal relations among changes of cerebral blood flow, which is commonly used as a measure of brain work, and the cerebral oxygen consumption rate as the precise measure of this work.
Publication Statistics
PubMed lists 427 full-length peer-reviewed papers May 2023.
Web of Science lists 853 papers with 24,779 citations and H-index 81.
Google Scholar lists 1025 papers with 35,917 citations and H-index 99.
Award recipient
1970 Copenhagen University Gold Medal in Medicine
1972 The American Cyanamid Corporation’s Lederle Award
1975 The Martin Salomonsen Award in Medical History, University of Copenhagen
1982 The Dannin Foundation Award for Outstanding Research in Science
1986 Bankier Henry Hansen’s Award, University of Copenhagen
1987 Anna Bochardt’s Award, Society of Medicine, Copenhagen
1992 Craigie Lecturer, 2nd Craigie Conference, Montreal, Canada
1995 Christenson-Ceson Family Foundation Award For Major Research Accomplishments, Danish Medical Association
1996 Magda Agathe Strunge’s Award, University of Aarhus
1998 Kuhl-Lassen Lecturer, Brain Imaging Council, Society of Nuclear Medicine
1999 Fellow, American Association for the Advancement of Science
2000 Grand Research Prize, International Order of Odd Fellows, Denmark
2000 Carl Krebs Honorary Award, Aarhus University Hospitals, Aarhus, Denmark
2003 Fellow, Royal Society of Canada
2004 Roy & Sherrington Award, Gordon Research Conferences, Colby College, Maine
2006 Danish Orthopedic Society Honorary Lecturer, Odense, Denmark
2009 Member, Academia Europaea (Academy of Europe),
2010 Global Excellence Award, Capital Region Hospitals, Denmark
2010 Chancellor’s Award Lecture in Neuroscience, Louisiana State University, New Orleans, Louisiana
2010 Erhoff Prize, Denmark
2011 Orr. E. Reynolds Award, American Physiological Society
2012 Research Communication Prize, Danish Ministry of Higher Education
2013 Alzheimer Foundation Research Prize, Denmark
2013 Niels A. Lassen Prize, Denmark
2014 Foreign Member, Norwegian Academy of Science and Letters, Norway 2014
Distinctions
Honorary Fellowships
- Royal Society of Canada.
- American Association for the Advancement of Science.
- American College of Neuropsychopharmacology.
Academic Memberships
- Academy of Europe.
- Norwegian Academy of Science and Letters
Latest Original Peer-Reviewed Papers
- Sigvard AK, Bojesen KB, Ambrosen KS, Nielsen MØ, Gjedde A, Tangmose K, Kumakura Y, Edden R, Dan Fuglø, Jensen LT, Rostrup E, Ebdrup BH, Glenthøj BY (2022). Dopamine Synthesis Capacity and GABA and Glutamate Levels Separate Antipsychotic-Naïve Patients With First-Episode Psychosis From Healthy Control Subjects in a Multimodal Prediction Model. Biological Psychiatry Global Open Science, 2022, ISSN 2667-1743, https://doi.org/10.1016/j.bpsgos.2022.05.004.
- Khodaii J, Araj-Khodaei M, Vafaee MS, Wong DF, Gjedde A (2022). Relative Strengths of Three Linearizations of Receptor Availability: Saturation, Inhibition, and Occupancy Plots. J Nucl Med. 2022 Feb;63(2):294-301. doi: 10.2967/jnumed.117.204453. Epub 2021 Jun 4. PMID: 34088774; PMCID: PMC8805780.
- Chang NHS, Kumakura Y, Møller A, Linnet J, Bender D, Doudet DJ, Vafaee MS, Gjedde A (2022). On the learning of addictive behavior: Sensation-seeking propensity predicts dopamine turnover in dorsal striatum. Brain Imaging Behav. 2022 Feb;16(1):355-365. doi: 10.1007/s11682-021-00509-5. Epub 2021 Aug 21. PMID: 34417966; PMCID: PMC8825434.
- Vestergaard MB, Ghanizada H, Lindberg U, Arngrim N, Paulson OB, Gjedde A, Ashina M, Larsson HBW (2022). Human Cerebral Perfusion, Oxygen Consumption, and Lactate Production in Response to Hypoxic Exposure. Cereb Cortex. 2022 Mar 4;32(6):1295-1306. doi: 10.1093/cercor/bhab294. PMID: 34448827; PMCID: PMC8924433.
- Rischel EB, Gejl M, Brock B, Rungby J, Gjedde A (2022). In Alzheimer’s disease, amyloid beta accumulation is a protective mechanism that ultimately fails. Alzheimers Dement. 2022 Jun 8. doi: 10.1002/alz.12701. Epub ahead of print. PMID: 35673950.
- Khodaii J, Nomura Y, Chang NHS, Wong DF, Møller A, Gjedde A (2022). Dopamine D2/3 Receptor Availabilities in Striatal and Extrastriatal Regions of the Adult Human Brain: Comparison of Four Methods of Analysis. Neurochem Res. 2022 Dec 16. doi: 10.1007/s11064-022-03825-4. Epub ahead of print. PMID: 36525123.
- Phan JA, Wong DF, Chang NHS, Kumakura Y, Bauer WR, Gjedde A (2022). Transient equilibrium determination of dopamine D2/D3 receptor densities and affinities in brain. Front. Nucl. Med., 01 December 2022 Sec. PET and SPECT https://doi.org/10.3389/fnume.2022.1030387
- Oka N, Sakoh M, Hirayama M, Niiyama M, Gjedde A (2023) Asymmetry of signal intensities of corticofugal tracts in T2-weighted brain images reflects manual dexterity. Scientific Reports accepted.
- Rossi R, Brentzen SL, Thomsen MB, Real CC, Wegener G, Grassi-Oliveira R, Gjedde A, Landau AM (2023) A single dose of cocaine increases SV2A density in hippocampus of adolescent rats. Acta Neuropsychiat accepted.
- Faber J, Ballegaard S, Ørsted N, Eldrup E, Karpatschof B, Gyntelberg F, Hecquet SK, Gjedde A (2023) In Type 2 Diabetes Mellitus, normalization of hemoglobin A1c accompanies reduced sensitivity to painful pressure at the sternum. Frontiers in Neuroscience, accepted.