Publications 1969-2023

Revised May 21, 2023

Bøger og hefter på dansk (Books and Booklets in Danish)

Peer-Reviewed Reports of Original Findings

• Copenhagen 1969-73
• New York 1973-76
• Copenhagen 1976-86
• Montreal 1986-94
• Aarhus 1994-2008
• Copenhagen 2008-2018
• Odense 2019-2020
• Copenhagen/Aarhus 2021-

Editorials, Perspectives, Published Protocols, and Reviews

Textbook Chapters

Review Chapters in Books

Abstracts in Conference Proceedings

• Copenhagen, New York & Cologne 1970-1986
• Montreal 1986-1994
• Aarhus 1994-2008
• Copenhagen 2008-2018
• Odense 2019-2020
• Copenhagen/Aarhus 2021-

Letters and Comments

History of Medicine and Obituaries

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Publication Statistics 2023

• PubMed and PMC 427 full-length peer-reviewed publications
• Web of Science all databases 848 publications, 24,573 citations, Hirsch Index 80
• Google Scholar collection 1,025 publications, 35,605 citations, Hirsch Index 99

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List of Publications

Bøger, breve og hefter på dansk (Books, Letters and Booklets in Danish)

1. Gjedde A (1971) Peter Ludvig Panums videnskabelige indsats [Scientific Accomplishments of Peter Ludvig Panum]. Monograph: Bibliotek for Læger, Copenhagen: DadL.

2. Melchior JC, Andreasen E, Brøchner-Mortensen K, Gjedde A, Møller-Christensen V, Trolle D (1979) (eds.) Københavns Universitet 1479-1979. Bind VII. Det lægevidenskabelige Fakultet. København: Københavns Universitet.

3. Møller-Christensen V, Gjedde A (1979) The medical school in Copenhagen from its start in 1479 to its union with the academy of surgeons in 1842 (in Danish: Det lægevidenskabelige Fakultet l479-1842). In: Københavns Universitet 1479-1979 (eds. Melchior J et al.), vol. 7, pp. 1-89.

4. Gjedde A (1998) Biparietale udfald ved Alzheimers sygdom. [Biparietal failure in Alzheimer’s disease] Ugeskr Laeger 160: 3236-3237

5. Gjedde A (1999) Peer review eller lodtrækning? [Peer review or lottery?] Ugeskr Laeger 161: 279

6. Johannsen P, Gjedde A (2000) PET-skanning og demensudredning. København: Pfizer A/S.

7. Gjedde A (2001) Normalvægt versus idealvægt [normal weight contra ideal weight]. Ugeskr Laeger 163: 3822-3824

8. Gjedde A (2002) Selvet i neurobiologisk betydning. I: Vinkler på Selvet – en antologi om selvbegrebets anvendelse i psykologien. Bertelsen P, Hermansen M, Tønnesvang J (red.), Klim, Aarhus, pp. 343-362.

9. Gjedde A (2003) PET i Århus. Et laboratoriums tilblivelse. In: På sporet af det indre liv. PET i Århus 1993-2003, Rodell AB (ed.). Professionelle og Eksperimenterende Tekster, Aarhus, pp. 5-18.

10. Gjedde A, Vafaee MS, Østergaard L (2003) PET og hjernearbejde. Energiforsyning og stofomsætning i hjernen. In: På sporet af det indre liv. PET i Århus 1993-2003, Rodell AB (ed.). Professionelle og Eksperimenterende Tekster, Aarhus, pp. 137-149.

11. Roepstorff A, Gjedde A (2003) Subjektivitet som eksperimentel variabel i hjerneskanningsforsøg. In: Subjektivitet og videnskab. Bevidsthedsforskning i det 21. Århundrede, Zahavi D, Christensen G (eds.). København: Roskilde Universitetsforlag, pp. 213-236.

12. Gjedde A (2003) Da videnskabskrigen kom til Danmark: Den medicinske virkelighed kontra den humanistiske relativisme. Bibl Læger 195: 252-255.

13. Gjedde A (2003) Bevidsthedens neurobiologi, pp. 21-34. Hjernen og bevidsthed. Brinch J, Bøgeskov J & Elleman K , eds.  København: HjerneForum.

14. Gjedde A (2004) Hjernens sprogcentrer og deres opdagelse, pp. 10–18. Hjernen og Sprog. Bøgeskov J, Elleman K, eds. København: HjerneForum,

15. Gjedde A (2005) Kønslivets neurobiologi, pp. Hjernen og seksualitet. Bøgeskov J, Elleman K, eds. København: HjerneForum.

16. Gjedde A (2006) Bedragerisk syn og hørelse, pp. 16-26. Hjernen vil bedrages. Bøgeskov J, Elleman K, eds. København: HjerneForum

17. Gjedde A (2006) [PET in Aarhus: the origins of a laboratory] Dan Medicinhist Arbog. 2006;34:156-178.

18. Gjedde A (2007) Peter Ludvig Panum (1820-1885). Ugeskrift for Læger 169: 2862 2007-g-27

19. Gjedde A (2007) Nikotin og alkohol, sex og religion, pp. 32-41. Den afhængige hjerne. Bøgeskov J, Ellemann K, eds. København: HjerneForum, .

20. Gjedde A (2008) Er jeg min hjerne? Om bevidsthedens sted, før, nu og i fremtiden, pp. 27-38. Hjernen – før, nu og i fremtiden. Bøgeskov J, Ellemann K, eds. København: HjerneForum, pp.

21. Gjedde A (2008) Hjernens “levende” billeder, pp.60-76. Hjernen – før, nu og i fremtiden. Bøgeskov J, Ellemann K, eds. København: HjerneForum.

22. Gjedde A (2008) Ondets rod: Om ondskabens neurobiologi. Tidsskriftet KVAN bind 82.

23. Kupers R, Ptito M, Gjedde A (2011) De plastiske sanser, pp. Den plastiske hjerne. Gade A, Nielsen JB, eds. København: HjerneForum,

24. Gjedde A, Nielsen JB, Martiny KMM (2015) Den menneskelige hjerne. Gjedde A, ed. København: HjerneForum

25. Gjedde A (2018) Bevægelserne og den aldrende hjerne, pp. Den aldrende hjerne eds. København: HjerneForum.

26. Gjedde A (2019) Kunstneriske dyrehjerner, pp. Den kunstneriske hjerme. eds. København: HjerneForum

27. Geday J & Gjedde A (2020) Hjernens betydning for kriminalitet, pp 9-25. Den kriminelle hjerne, Rasmussen RS og Sørensen TA, eds.  København: HjerneForum

28. Gjedde A (2020) Hjernen og kriminaliteten. Lægemagasinet 3/2020 pp. 20-33.

29. Gjedde A (2020) De syv små djævle. Weekendavisen, IDEER p. 13, 13/11/2020.

30. Gjedde A (2021) Global pandemi og rund fødselsdag har gjort medicinsk pioner relevant igen. Dagens Medicin 5/2021 pp. 30-31.

31. Gjedde A (2021) Hjernens hemmeligheder. Weekendavisen, IDEER p. 7, 15/1/2021.

32. Gjedde A (2022) Minder om fremtiden, pp. 116-125. Hjernen og hukommelsen. Sørensen TA, Gjedde A, Rasmussen RS, eds. København: HjerneForum.

Peer-Reviewed Reports of Original Findings

Copenhagen 1969-73

1. Gjedde A, Crone C (1975) Induction processes in blood-brain transfer of ketone bodies during starvation. Am J Physiol 229: 1165-1169.

2. Gjedde A, Andersson J, Eklöf B (1975) Brain uptake of lactate, antipyrine, water and ethanol. Acta Physiol Scand 93: 145-149.

New York 1973-76

3. Gjedde A, Caronna JJ, Hindfelt B, Plum F (1975) Whole-brain blood flow and oxygen metabolism in the rat during nitrous oxide anesthesia. Am J Physiol 229: 113-118.

4. Gjedde A, Hindfelt B (1975) Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia. Acta Anaesthesiol Scand 19: 310-315.

5. Gjedde A, de la Monte SM, Caronna JJ (1977) Cerebral blood flow and oxygen consumption in rat, measured with microspheres or xenon. Acta Physiol Scand 100: 273-281.

6. Gjedde A, Lockwood A, Duffy TE, Plum F (1978) Cerebral blood flow and metabolism in chronically hyperammonemic rats: Effect of an acute ammonia challenge. Ann Neurol 3: 325-330.

7. Gregoire NM, Gjedde A, Plum F, Duffy TE (1978) Cerebral blood flow and cerebral metabolic rates for oxygen, glucose, and ketone bodies in new-born dogs. J Neurochem 30: 63-69.

Copenhagen 1976-86

8. Gjedde A, Gundtoft O, Svane H (1978) Deep sedative hypothermia (in Danish: Dyb sedativ hypotermi). Ugeskr Læger 140: 1408-1411.

9. Gjedde A, Hansen AJ, Siemkowicz E (1980) Rapid simultaneous determination of regional blood flow and blood-brain glucose transfer in brain of rat. Acta Physiol Scand 108: 321-330.

10. Gjedde A (1980) Rapid steady-state analysis of blood-brain glucoser transfer in rat. Acta Physiol Scand 108: 331-339.

11. Hansen AJ, Quistorff B, Gjedde A (1980) Relationship between local changes in cortical blood flow and extracellular K+ during spreading depression. Acta Physiol Scand 109: 1-6.

12. Gjedde SB, Gjedde A (1980) Organ blood flow rates and cardiac output of the BALB/c mouse. Comp Biochem Physiol 67A: 671-674.

13. Siemkowicz E, Gjedde A (1980) Post-ischemic coma in rat: Effect of different pre-ischemic blood glucose levels on cerebral metabolic recovery after ischemia. Acta Physiol Scand 110: 225-232.

14. Gjedde A, Rasmussen M (1980) Blood-brain glucose transport in the conscious rat: Comparison of the intravenous and intracarotid injection methods. J Neurochem 35: 1375-1381.

15. Gjedde A, Rasmussen M (1980) Pentobarbital anesthesia reduces blood-brain glucose transfer in the rat. J Neurochem 35: 1382-1387.

16. Hansen AJ, Gjedde A, Siemkowicz E (1980) Extracellular potassium and blood flow in the post-ischemic rat brain. Pflugers Arch 389: 1-7.

17. Gjedde A (1981) High- and low-affinity transport of D-glucose from blood to brain. J Neurochem 36: 1463-1471.

18. Gjedde A, Hansen AJ, Quistorff B (1981) Blood-brain glucose transfer in spreading depression. J Neurochem 37: 807-812.

19. Christensen TG, Diemer NH, Laursen H, Gjedde A (1981) Starvation accelerates blood-brain glucose transfer. Acta Physiol Scand 112: 221-223.

20. Gjedde A, Crone C (1981) Blood-brain glucose transfer: Repression in chronic hyperglycemia. Science 214: 456-457.

21. Lauritzen M, Jørgensen MB, Diemer NH, Gjedde A, Hansen AJ (1982) Persistent oligemia of rat cerebral cortex in the wake of spreading depression. Ann Neurol 12: 469-474.

22. GjeddeA (1982) Calculation of glucose phosphorylation from brain uptake of glucose analogs in vivo: A re-examination. Brain Res Rev 4: 237-274.

23. Siemkowicz E, Hansen AJ, Gjedde A (1982) Hyperglycemic ischemia of rat brain: The effect of post-ischemic insulin on metabolic rate. Brain Res 243: 386-390.

24. Gjedde A (1982) The blood-brain barrier is impermeable to metrizamide. Acta Neurol Scand 66: 392-395.

25. Font C, Garcia-Campos M, Hansen AJ, Siemkowicz E, Gjedde A (1982) Constantes de difusion de inositol en cerebro de ratas. Laboratorio (Granada) 73: 499-506.

26. Gjedde A, Diemer NH (1983) Autoradiographic determination of regional brain glucose content J Cereb Blood Flow Metab 3: 303-310.

27. Gjedde A, Christensen O (1984) Estimates of Michaelis-Menten constants for the two membranes of the brain endothelium. J Cereb Blood Flow Metab 4: 241-249.

28. Bech L, Diemer NH, Gjedde A (1984) The effect of metrizamide on regional brain glucose metabolism in the rat. Acta Neurol Scand 69: 249-253.

29. Gjedde A: (1984) On the measurement of glucose in brain. Neurochem Res 9: 1667-1671.

30. Gjedde A (1984) Blood-brain transport of galactose in experimental galactosemia. With special reference to the competitive interaction between galactose and glucose. J Neurochem 43: 1654-1662.

31. Wong D, Wagner HN, Dannals RF, Links JM, Frost JJ, Ravert HT, Wilson AA, Rosenbaum AE, Gjedde A, Douglass KH, Petronis JD, Folstein MF, Toung JKT, Burns HD, Kuhar MJ (1984) Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain. Science 226: 1393-1396.

32. Gjedde A, Diemer NH (1985) A double tracer study of the fine regional blood-brain glucose transfer in the rat by computer-assisted autoradiography (CAA). J Cereb Blood Flow Metab 5: 163-178.

33. Gjedde A, Wienhard K, Heiss W-D, Kloster G, Diemer NH, Herholz K, Pawlik G: (1985) Comparative regional analysis of 2-fluorodeoxyglucose and methylglucose uptake in brain of four stroke patients. J Cereb Blood Flow Metab 5: 282-289.

34. Andersen A, Waaben J, Husum B, Voldby B, Bødker A, Hansen AJ, Gjedde A (1985) Non-pulsatile cardiopulmonary bypass disrupts the flow-metabolism couple in brain. J Thorac Cardiovasc Surg 40: 570-579.

35. Bech L, Diemer NH, Gjedde A (1985) Metabolic effect of topical application of metrizamide to rat brain cortex. Acta Neurol Scand 72: 427-431.

36. Wong DF, Gjedde A, Wagner HNJr: (1986) Quantification of neuroreceptors in the living human brain. I: Irreversible binding. J Cereb Blood Flow Metab 6: 137-146.

37. Wong DF, Gjedde A, Wagner HNJr, Dannals RF, Douglass KH, Links JM, Kuhar MJ (1986) Quantification of neuroreceptors in the living human brain. II: Inhibition studies of receptor density. J Cereb Blood Flow Metab 6: 147-153.

38. Fuglsang A, Lomholt M, Gjedde A (1986) Blood-brain transfer of glucose and glucose analogs in newborn rats. J Neurochem 46: 1417-1428.

39. Kretzschmar R, Landgraf R, Gjedde A, Ermisch A (1986) Vasopressin binds to microvessels from rat hippocampus. Brain Res 380: 325-330.

40. Nedergaard M, Gjedde A, Diemer NH (1986) Focal ischemia of the rat brain: Autoradiographic determination of cerebral glucose utilization, glucose content and blood flow. J Cereb Blood Flow Metab 6: 414-424.

41. Wong DF, Wagner HNJr, Links JM, Kuhar MJ, Gjedde A (1986) Human brain receptor distribution. Science 232: 1269-1271.

42. Wong DF, Wagner HNJr, Tune LE, Dannals RF, Pearlson GD, Links JM, Tamminga CA, Broussole EP, Ravert HT, Wilson AA, Toung JKT, Malat J, Williams JA, O’Tuama LA, Snyder SH, Kuhar MJ, Gjedde A (1986) Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics. Science 234: 1558-1563.

43. Reith J, Ermisch A, and Gjedde A (1986) Saturable vasopressin retention in hippocampal endothelium and in non-BBB brain regions (pineal and pituitary gland s). Wiss. Z. Karl Marx Univ. 36: 87-90.

44. Reith J, Ermisch A, Diemer NH, Gjedde A (1987) Saturable retention of vasopressin by hippocampus vessels in vivo, associated with inhibition of blood-brain transfer of large neutral amino acids. J Neurochem 49: 1471-1479.

45. Nedergaard M, Gjedde A, Diemer NH (1987) Hyperglycemia protects against neuronal injury around experimental brain infarcts. Neurol Res 9: 241-244.

Montreal 1986-94

46. Redies C, Diksic M, Evans AC, Gjedde A, Yamamoto YL (1987) Double-label autoradiographic deoxyglucose method for sequential measurement of regional cerebral glucose utilization. Neurosci 22: 601-619.

47. Brøndsted HE, Gjedde A (1988) Measuring brain glucose phosphorylation with labeled glucose. Am J Physiol 254: E443-E448.

48. Rahbek Sørensen H, Husum B, Waaben J, Andersen K, Andersen LI, Gefke K, Kaarsen AL, Gjedde A (1988) Brain microvascular function during cardiopulmonary bypass. J Thorac Cardiovasc Surg 94: 727-732.

49. Redies C, Diksic M, Collier B, Gjedde A, Thompson CJ, Gauthier S, Feindel WH (1988) Influx of a choline analog to dog brain measured by PET. Synapse 2: 406-411.

50. Waaben J, Husum B, Hansen AJ, Gjedde A (1989) Local cerebral blood flow and glucose utilization during hyperventilation and adenosine-induced hypotension in the rat. Anesthesiology 70: 299-304.

51. Dyve, SE, Gjedde A, Diksic M, Sherwin A, Hakim AM (1989) In vivo quantification of blood-brain transfer and binding of (125I)heat, an alpha-1 adrenoceptor antagonist. Synapse 3: 205-212.

52. Waaben J, Husum B, Hansen AJ, Gjedde A (1989) Hypocapnia prevents the decrease in local cerebral metabolism during isoflurane-induced hypotension. J Neurosurg Anesthesiol 1: 29-34.

53. Hakim AM, Evans AC, Berger L, Kuwabara H, Worsely K, Marchal G, Beil C, Pokrupa R, Diksic M, Meyer E, Gjedde A, Marrett S (1989) The effect of nimodipine on the evolution of human cerebral infarction studied by PET. J Cereb Blood Flow Metab 9: 523-534.

54. Redies C, Hoffer LJ, Beil C, Marliss EB, Evans AC, Lariviere F, Marrett S, Meyer E, Diksic M, Gjedde A, Hakim AM (1989) Generalized decrease in brain glucose metabolism during fasting in humans studied by pet. Am J Physiol 256: E805-E810.

55. Gjedde A, Evans AC (1989) PET studies of domoic acid poisoning in humans: Excitotoxic destruction of brain glutamatergic pathways, revealed in measurements of glucose metabolism by positron emission tomography. In: Domoic Acid Toxicity: Canada Diseases Weekly Volume 16S1E, pp. 105-109.

56. Kuwabara H, Evans AC, Gjedde A (1990) Michaelis-Menten constraints improved cerebral glucose metabolism and  regional lumped constant measurements with [18F]fluorodeoxyglucose. J Cereb Blood Flow Metab 10: 180-189.

57. Gjedde A, Kuwabara H, Hakim A (1990) Reduction of functional capillary density in human brain after stroke. J Cereb Blood Flow Metab 10: 317-316.

58. Teitelbaum JS, Zatorre RJ, Carpenter S, Gendron D, Evans AC, Gjedde A, Cashman NR (1990) Neurological sequelae of domoic acid intoxication due to ingestion of mussels from Prince Edward Island. N Eng J Med 322: 1781-1787.

59. Brøndsted HE, Reith J, Gjedde A (1990) Regional glucose phosphorylation rate in brain during acute ethanol intoxication. Acta Neurol Scand 81: 229-231.

60. Brøndsted HE, and Gjedde A (1990) Phosphorylation rate in rat brain during normoglycemia, hypoglycemia, acute hyperglycemia and in diabetes-prone rats. Acta Neurol Scand 81: 233-236.

61. Reith J, Dyve S, Kuwabara H, Guttman M, Diksic M, Gjedde A (1990) Blood-brain transfer and metabolism of 6-[18F]fluoro-l-dopa. J Cereb Blood Flow Metab 10: 707-719, 1990.

62. Dyve S, Gjedde A (1991) Glucose metabolism of fetal rat brain in utero, measured with labeled deoxyglucose. Acta Neurol Scand 83: 14-19.

63. Hogan MJ, Gjedde A, Hakim AM (1991) Activity of the dihydorpyridine calcium channels following cerebral ischemia. Arzneim Forsch/Drug Res 41(I) nr.3a: 332-333.

64. Kuwabara H, Gjedde A (1991) Measurements of glucose phosphorylation with FDG are not affected by dephosphorylation of FDG-6-phosphate. J Nucl Med 32: 692-698.

65. Gjedde A, Reith J, Dyve S, Leger G, Guttman M, Diksic M, Evans AC, Kuwabara H (1991) dopa decarboxylase activity of the living human brain. Proc Nat Acad Sci (USA) 88: 2721-2725.

66. Thompson CJ, Ranger N, Evans AC, Gjedde A (1991) Validation of simultaneous PET emission and transmission scans. J Nucl Med 32: 154-160.

67. Blomqvist G, Gjedde A, Gutniak M, Grill V, Widen L, Stone-Elander S, Hellstrand E (1991) Facilitated transport of glucose from blood to brain in man and the effect of moderate hypoglycemia on cerebral glucose utilization. Eur J Nucl Med 18: 834-837.

68. Gjedde A, Dyve S, Yang Y-J, McHugh M, Pappius M (1991) Bi-Affinity alpha-1 adrenoceptor binding in normal rat brain in vivo. Synapse 9: 1-6.

69. Hogan MJ, Gjedde A, Hakim AM (1991) In-vivo binding of nimodipine in brain II. Binding kinetics in focal cerebral ischemia. J Cereb Blood Flow Metab 11: 771-778.

70. Brust P, Baethmann A, Gjedde A, Ermisch A (1991) Atrial natriuretic peptide augments the blood-brain transfer of water but not leucine and glucose. Brain Res 564: 91-96.

71. Ohta S, Meyer E, Thompson CJ and Gjedde A (1992) Oxygen consumption of the living human brain measured after a single inhalation of positron emitting oxygen. J Cereb Blood Flow Metab 12: 179-192.

72. Hogan MJ, Gjedde A, Hakim AM (1992) The in-vivo distribution of CGS-19755 within brain in a model of focal cerebral ischemia. J Neurochem 58: 186-191.

73. Guttman M, Leger G, Cederbaum JM, Reches A, Woodward W, Evans A, Diksic M, Gjedde A (1992) 3-O-methyldopa administration does not alter fluorodopa transport into the brain. Ann Neurol 31: 638-643.

74. Brust P, Shaya EK, Jeffries KJ, Dannals RF, Ravert HT, Wilson AA, Conti PS, Wagner Jr. HN, Gjedde A, Ermisch A, Wong DF (1992) Effects of vasopressin on blood-brain transfer of L-[11C]methionine in dogs. J Neurochem 59: 1421-1429.

75. Zatorre R, Evans AC, Meyer E, Gjedde A (1992) Lateralization of phonetic and pitch discrimination in speech processing. Science 256: 846-849.

76. Spencer D, Robbins R, Naftolin F, Marek K, Vollmer T, Leranth C, Roth R, Price L, Gjedde A, Bunney B, Sass K, Elsworth J, Kier E, Makuch R, Hoffer P, Redmond D (1992) Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson’s disease. New Engl J Med 327: 1541-1548.

77. Kuwabara H, Cumming P, Reith J, L´eger G, Diksic M, Evans A, Gjedde A (1993) Human striatal L-DOPA decarboxylase activity estimated in vivo using 6-[18F]fluoro-DOPA and positron emission tomography: Error analysis and application to normal subjects. J Cereb Blood Flow Metab 13: 43-56.

78. Hoshi H, Kuwabara H, L´eger G, Cumming P, Guttman M, Gjedde A (1993) 6-[18F]fluoro-L-DOPA metabolism in living human brain: A comparison of six analytical methods. J Cereb Blood Flow Metab 13: 57-69.

79. Gjedde A, Kuwabara H (1993) Absent recruitment of capillaries in brain tissue recovering from stroke. Acta Neurochir 57: 35-40.

80. Cumming P, L´eger GC, Kuwabara H, Gjedde A (1993) Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine
([18F]FDOPA) in humans. J Cereb Blood Flow Metab 13: 668-675.

81. Guttman M, Leger G, Reches A, Evans A, Kuwabara H, Cedarbaum JM, Gjedde A (1993) Administration of the new comt inhibitor OR-611 increases striatal uptake of fluorodopa. Movement Disorders 8: 298-304.

82. Gjedde A, Leger G, Cumming P, Yasuhara Y, Evans AC, Guttman M, Kuwabara H (1993) Striatal L-DOPA decarboxylase activity in Parkinson’s disease in vivo: Implications for the regulation of dopamine synthesis. J Neurochem 61: 1538-1541.

83. Takada A, Grdiˇsa N, Diksic M, Gjedde A, Yamamoto YL (1993) Rapid steady-state analysis of blood-brain transfer of L-tryptophan in rat, with special reference to the plasma protein binding. Neurochem Int 23: 351-359.

84. Cumming P, Gjedde A (1993) Kinetics of the uptake of [3H]paroxetine in the rat brain. Synapse 15: 124-129.

85. Cumming P, Vincent S, Gjedde A (1994) Histamine H3 binding sites in the rat brain: Localization in the nucleus solitary tract. Brain Res 641: 198-202.

86. Cumming P, Gjedde A (1994) Subclasses of histamine H3 binding sites in the rat brain. Brain Res 641: 203-207.

87. Waaben J, Sørensen HR, Andersen UL, Gefke K, Lund J, Aggestrup S, Laursen H, Gjedde A (1994) Brain damage following low flow cardiopulmonary bypass in pigs. Eur J Cardio-Thoracic Surg 8: 91-96.

88. Waaben J, Sørensen HR, Andersen UL, Gefke K, Lund J, Aggestrup S, Laursen H, Gjedde A (1994) Arterial line filtration protects brain microcirculation during cardiopulmonary bypass. J Thorac Cardiovasc Surg 107: 1030-1035.

89. Cumming P, Kuwabara H, Gjedde A (1994) Kinetic analysis of 6-[18F]fluoro-L-dihydroxyphenyl-alanine ([18F]DOPA) metabolism in the rat. J Neurochem 63: 1675-1682.

90. Cumming P, Venkatachalam TK, Rajagopal S, Diksic M, Gjedde A (1994) Kinetics of the cerebral uptake of alpha-[14C]methyl-para-tyrosine in the rat. Synapse 17: 125-128.

91. Zeitouni AG, Yamamoto YL, Black M, Gjedde A (1994) Functional imaging of head and neck tumors using positron emission tomography. J Otolaryngol 23: 77-80.

92. Berger R, Gjedde A, Heck J, M¨uller E, Krieglstein J, Jensen A (1994) Extension of the 2-deoxyglucose method to the fetus in utero: Theory and normal values for the cerebral glucose consumption in fetal guinea pigs. J Neurochem 63: 271-279.

93. Coghill RC, Talbot JD, Evans AC, Meyer E, Gjedde A, Bushnell MC, Duncan GH (1994) Distributed processing of pain and vibration by the human brain. J Neuroscience 14: 4095-4108.

94. Cumming P, Lalibert´e C, Gjedde A (1994) Distribution of histamine H3 binding in forebrain of mouse and guinea pig. Brain Res 664: 276-279.

95. Reith J, Benkelfat C, Sherwin A, Yasuhara Y, Kuwabara H, Andermann F, Bachneff S, Cumming P, Diksic M, Dyve S, Etienne P, Evans A, Lal S, Shevell M, Savard G,Wong D, Chouinard G, Gjedde A (1994) Elevated dopa decarboxylase activity in living brain of patients with psychosis. Proc Nat Acad Sci USA 91: 11651-11654.

96. Benkelfat C, Bradwejn J, Meyer E, Ellenbogen M, Milot S, Gjedde A, Evans A (1995) Functional neuroanatomy of CCK4-induced anxiety in normal healthy volunteers. Am J Psychiat 152: 1180-1184.

97. Cumming P, Ase A, Diksic M, Harrison J, Kuwabara H, Laliberte C, Gjedde A (1995) Metabolism and blood-brain clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat. Biochem Pharmacol 50: 943-946.

98. Cumming P, Kuwabara H, Ase A, Gjedde A (1995) Regulation of DOPA decarboxylase activity in brain of living rat. J Neurochem 65: 1381-1390.

99. Dyve S, Yang Y-J, McHugh M, Gjedde A, Pappius H (1995) Effect of injury on the bi-affinity alpha-1-adrenoceptor binding in the rat brain in vivo. Synapse 19: 88-96.

100. Kuwabara H, Cumming P, Yasuhara Y, Leger G, Guttman M, Diksic M, Evans AC, Gjedde A (1995) Regional striatal DOPA transport and decarboxylation activity in Parkinson’s disease. J Nucl Med 36: 1226-1231.

101. Wang GJ, Volkow ND, Logan J, Fowler JS, Schlyer D, MacGregor RR. Hitzemann RJ, Gjedde A, Wolf AP (1995) Serotonin 5-HT2 receptor availability in chronic cocaine abusers. Life Sciences 56: PL299-303.

102. Ohta S, Meyer E, Fujita H, Reutens DC, Evans A, Gjedde A (1996) Cerebral [O-15]water clearance in humans determined by PET. I. Theory and normal values. J Cereb Blood Flow Metab 16: 765-780.

103. Murase K, Kuwabara H, Yasuhara Y, Evans AC, Gjedde A (1996) Mapping of change in cerebral glucose utilization using fluorine-18 fluorodeoxyglucose double injection and the constrained weighted-integration method. IEEE Transact Med Imag 15: 824-835.

104. Reutens DC, McHugh MD, Toussaint PJ, Evans AC, Gjedde A, Meyer E. Stewart DJ (1997) l-Arginine infusion increases basal but not activated cerebral blood flow in humans. J Cereb Blood Flow Metab 17: 309-315.

Aarhus 1994-2008

105. Gee AD, Smith DF, Gjedde A (1995) The synthesis of [O-methyl-11C]venlafaxine: A potential tracer of the 5-HT reuptake site. J Labelled Comp Radiopharm 37: 309-310.

106. Wong DF, Harris JC, Naidu S, Yokoi F, Marenco S, Dannals RF, Ravert HT, Yaster M, Evans A, Rousset O, Bryan RN, Gjedde A, Kuhar MJ, Breese GR (1996) Dopamine transporters are markedly reduced in Lesch-Nyhan Disease in vivo. Proc Nat Acad Sci USA 93: 5539-5543.

107. Berger R, Gjedde A, Rischke R, Müller E, Heck J, Krieglstein J, Jensen A (1996) Local cerebral glucose utilization in fetal guinea pigs at 0.75 gestation. Eur J Obstet Gynecol Reprod Biol 66: 175-178.

108. Møller N, Frystyk J, Skjærbæk C, Pedersen HB, Christensen C, Schmitz O, Gee A, Gjedde A, Zapf J, Ørskov H (1996) Systemic and regional tumour metabolism in a patient with non-islet cell tumour hypoglycemia – role of increased levels of free insulin-like growth factors. Diabetologia 39: 1534-1535.

109. Bøtker HE, B¨ottcher M, Schmitz O, Gee A, Hansen SB, Cold GE, Nielsen TT, Gjedde A (1997) Glucose uptake and lumped constant variability in normal human hearts determined with [F-18]fluorodeoxyglucose. J Nucl Cardiol 4: 125-132.

110. Wong DF, Young D, Wilson PD, Meltzer CC, Gjedde A (1997) Quantification of neuroreceptors in the living human brain .3. D-2-like dopamine receptors – theory, validation, and changes during normal aging. J Cereb Blood Flow Metab 17: 316-330.

111. Wong DF, Pearlson GD, Tune LE, Young LT, Meltzer CC, Dannals RF. Ravert HT, Reith J, Kuhar MJ, Gjedde A (1997) Quantification of neuroreceptors in the living human brain .4. effect of aging and elevations of D-2-like receptors in schizophrenia and bipolar illness. J Cereb Blood Flow Metab 17: 331-342.

112. Berger R, Gjedde A, Hargarter L, Hargarter S, Krieglstein J, Jensen A (1997) Regional cerebral glucose utilization in immature fetal guinea pigs during maternal isocapnic hypoxemia. Pediat Res 42: 311-316.

113. Wong DF, Singer HS, Brandt J, Shaya E, Chen C, Brown J, Kimball AW. Gjedde A, Dannals RF, Ravert HT, Wilson PD, Wagner HN (1997) D2-like dopamine receptor density in tourette syndrome measured by pet. J Nucl Med 38: 1243-1247.

114. Smith DF, Jensen PN, Gee AD, Hansen SB, Danielsen E, Andersen F. Saiz PA, Gjedde A (1997) PET neuroimaging with [C-11]venlafaxine – serotonin uptake inhibition, biodistribution and binding in living pig brain. Eur Neuropsychopharmacol 7: 195-200

115. Johannsen P, Jakobsen JK, Gjedde A, Christensen T Gulmann NC, Abelskov KE, Ehlers L (1997) [A clinic for the study of dementia — 110 consecutive patients.] Ugeskr Laeger 159: 1246-1251

116. Cumming P, Ase A, Laliberte C, Kuwabara H, Gjedde A (1997) In vivo regulation of DOPA decarboxylase by dopamine receptors in rat brain. J Cereb Blood Flow Metab 17: 1254-1260.

117. Johannsen P, Jakobsen J, Bruhn P, Hansen SB, Gee A, Stødkilde-Jørgensen H, Gjedde A (1997) Cortical sites of sustained and divided attention in normal elderly humans. Neuroimage. 6: 145-155.

118. Deep P. Gjedde A. Cumming P. (1997) On the accuracy of an [F-18]FDOPA compartmental model – evidence for vesicular storage of [F-18]fluorodopamine in vivo. J Neurosci Meth 76: 157-165

119. Deep P. Kuwabara H. Gjedde A. Cumming P. (1997) The kinetic behaviour of [3H]DOPA in living rat brain investigated by compartmental modelling of static autoradiograms. J Neurosci Meth 78: 157-168

120. Gee AD. Moldt P. Gjedde A. (1997) The labelling of a novel tropane derivative [C-11]NS 2214 (BMS-204756) – an inhibitor of the dopamine transporter. J Label Comp & Radiopharm 39: 959-972

121. Poulsen PH, Smith DF, Østergaard L, Danielsen EH, Gee A, Hansen SB, Astrup J, Gjedde A (1997) In vivo estimation of cerebral blood flow, oxygen consumption and glucose metabolism in the pig by [o-15]water injection, [15O]oxygen inhalation and dual injections of [F-18]fluoro-deoxyglucose. J Neurosci Meth 77: 199-209

122. Reutens DC, Gjedde A, Meyer E (1998) Regional lumped constant differences and asymmetry in fluorine-18-FDG uptake in temporal lobe epilepsy. J Nucl Med 39: 176-180.

123. Cumming P, Gjedde A (1998) Compartmental analysis of dopa decarboxylation in living brain from dynamic positron emission tomograms. Synapse (New York) 29: 37-61.

124. Østergaard L, Smith DF, Vestergaard-Poulsen P, Hansen SB, Gee AD, Gjedde A, Gyldensted C (1998) Absolute cerebral blood flow and blood volume measured by magnetic resonance imaging bolus tracking: comparison with positron emission tomography values. J Cereb Blood Flow Metab 18: 425-432

125. Reith J, Cumming P, Gjedde A (1998) Enhanced [3H]DOPA and [3H]dopamine turnover in striatum and frontal cortex in vivo linked to glutamate receptor antagonism. J Neurochem 70: 1979-1985.

126. Cumming P, Ase A, Kuwabara H, Gjedde A, (1998) [3H]Dopa formed from [h-3]tyrosine in living rat brain is not committed to dopamine synthesis, J Cereb Blood Flow Metab 18: 491-499

127. Pedersen JR, Johannsen P, Bak CK, Kofoed B, Saermark K, Gjedde A (1998) Origin of Human Motor Readiness Field Linked to Left Middle Frontal Gyrus by MEG and PET. Neuroimage 8: 214-220

128. Østergaard L, Johannsen P, Host-Poulsen P Vestergaard-Poulsen P; Asboe H, Gee AD, Hansen SB, Cold GE, Gjedde A, Gyldensted C. (1998) Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: comparison with [(15)O]H2O positron emission tomography in humans. J Cereb Blood Flow Metab 18: 935-940

129. Léger G, Gjedde A, Kuwabara H, Guttman M, Cumming P (1998) Effect of catechol-O-methyltransferase inhibition on brain uptake of [18F]fluorodopa: Implications for compartmental modelling and clinical usefulness. Synapse 30: 351-361.

130. Svensson P, Johannsen P, Jensen TS, Arendt-Nielsen L, Nielsen J, Stødkilde-Jørgensen H, Gee AD, Hansen SB, Gjedde A (1998) Cerebral blood flow changes evoked by two levels of painful tonic and phasic heat stimulation: A positron emission tomography study. Eur J Pain 2: 95-107

131. Vafaee M, Meyer E, Marrett S, Evans AC, Gjedde A (1998) Increased oxygen consumption in human visual cortex: Response to visual stimulation. Acta Neurol Scand 98: 85-89.

132. Ptito M, Johannsen P, Faubert J, Gjedde A (1999) Activation of human extrageniculostriate pathways after damage to area V1.Neuroimage 9: 97-107

133. Ohta S, Reutens DC, Gjedde A (1999) Brief vibrotactile stimulation does not increase cortical oxygen consumption when measured by single inhalation of positron emitting oxygen. J Cereb Blood Flow Metab 19: 260-265

134. Fujita H, Kuwabara H, Reutens DC, Gjedde A (1999) Oxygen consumption of cerebral cortex fails to increase during continued vibrotactile stimulation. J Cereb Blood Flow Metab 19: 266-271

135. Vafaee MS, Meyer E, Marrett S, Paus T, Evans AC, Gjedde A. (1999) Frequency-dependent changes in cerebral metabolic rate of oxygen during activation of human visual cortex. J Cereb Blood Flow Metab 19: 272-277

136. Ptito M, Dalby M, Gjedde A. (1999) Visual field recovery in a patient with bilateral occipital lobe damage. Acta Neurol Scand 99: 252-254

137. Cumming P, Reith J, Gjedde A (1999) Cocaine withdrawal and the cerebral influx of [18F]fluoro-L-DOPA (FDOPA). Neuropsychopharmacology 20: 395-398

138. Smith DF, Gee AD, Hansen SB, Moldt P, Nielsen EO, Scheel-Kruger J, Gjedde A (1999) Uptake and distribution of a new SSRI, NS2381, studied by PET in living porcine brain. Eur Neuropsychopharmacol 9: 351-359

139. Danielsen EH, Smith DF, Gee AD, Venkatachalam TK Hansen SB, Hermansen F, Gjedde A, Cumming P (1999) Cerebral 6-[(18)F]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography. Synapse 33: 247-258

140. Borbely K, Brooks RA, Wong DF, Burns RS, Cumming P, Gjedde A, Di Chiro G (1999) NMSP binding to dopamine and serotonin receptors in MPTP-induced parkinsonism: relation to dopa therapy. Acta Neurol Scand 100: 42-52

141. Bøtker HE, Goodwin GW, Holden JE, Doenst T, Gjedde A, Taegtmeyer H (1999) Myocardial glucose uptake measured with fluorodeoxyglucose: a proposed method to account for variable lumped constants. J Nucl Med 40: 1186-1196

142. Mirz F, Pedersen CB, Ishizu K, Johannsen P, Ovesen T, Stødkilde-Jørgensen H, Gjedde A (1999) Positron emission tomography of cortical centers of tinnitus. Hear Res 134: 133-144.

143. Wiggers H, B¨ottcher M, Nielsen TT, Gjedde A, Bøtker HE (1999) Measurement of myocardial glucose uptake in patients with ischemic cardiomyopathy: application of a new quantitative method using regional tracer kinetic information. J Nucl Med 40: 1292-300

144. Johannsen P, Jakobsen J, Bruhn P, Gjedde A (1999) Cortical responsesto sustained and divided attention in Alzheimer’s disease. Neuroimage 10: 269-281

145. Mirz F, Ovesen T, Ishizu K, Johannsen P, Madsen S, Gjedde A, Pedersen CB (1999) Stimulus-dependent central processing of auditory stimuli: a PET study. Scand Audiol 28: 161-169.

146. Cumming P, Yokoi F, Chen A, Deep P, Dagher A, Reutens D, Kapczinski F, Wong DF, Gjedde A (1999) Pharmacokinetics of radiotracers in human plasma during positron emission tomography. Synapse 34: 124-134

147. Deep P, Dagher A, Sadikot A, Gjedde A, Cumming P (1999) Stimulation of dopa decarboxylase activity in striatum of healthy human brain secondary to NMDA receptor antagonism with a low dose of amantadine. Synapse 34: 313-318

148. Mirz F, Gjedde A, Stødkilde-Jørgensen H, Pedersen CB (2000) Functional brain imaging of tinnitus-like perception induced by aversive auditory stimuli. NeuroReport 11: 633-637

149. Vafaee MS, Gjedde A (2000) Model of blood-brain transfer of oxygen explains non-linear flow-metabolism coupling during stimulation of visual cortex. J Cereb Blood Flow Metab 20: 747-754.

150. Pedersen CB, Mirz F, Ovesen T, Ishizu K, Johannsen P, Madsen S, Gjedde A (2000) Cortical centres underlying auditory temporal processing in humans: a PET study. Audiology 39: 30-37.

151. Danielsen EH, Cumming P, Andersen F, Bender D, Brevig T, Falborg L, Gee A, Gillings NM, Hansen SB, Hermansen F, Johansen J, Johansen TE, Dahl-Jørgensen A, Jørgensen HA, Meyer M, Munk O, Pedersen EB, Poulsen PH, Rodell AB, Sakoh M, Simonsen CZ, Smith DF, Sørensen JC, stergard L, Zimmer J, Gjedde A (2000) The DaNeX study of embryonic mesencephalic, dopaminergic tissue grafted to a minipig model of Parkinson’s disease: Preliminary findings of effect of MPTP poisoning on striatal dopaminergic markers. Cell Transplant 9: 247-259.

152. Bøtker HE, Wiggers H, Bøttcher M, Christiansen JS, Nielsen TT, Gjedde A, Schmitz O (2000) Short-term effects of growth hormone on myocardial glucose uptake in healthy humans. Am J Physiol (EndocrinolMetab) 278: E1053-E1059.

153. Rousset OG, Deep P, Kuwabara H, Evans AC, Gjedde A, Cumming P (2000) Effect of partial volume correction on estimates of the influx and cerebral metabolism of 6-[(18)F]fluoro-L-dopa studied with PET in normal control and Parkinson’s disease subjects. Synapse 37: 81-89.

154. Kupers RC, Gybels JM, Gjedde A (2000) Positron emission tomography study of a chronic pain patient successfully treated with somatosensory thalamic stimulation. Pain 87: 295-302.

155. Ishizu K, Smith DF, Bender D, Danielsen E, Hansen SB, Wong DF, Cumming P, Gjedde A (2000) Positron emission tomography of radioligand binding in porcine striatum in vivo: Haloperidol inhibition linked to endogenous ligand release. Synapse 38: 87-101.

156. Sakoh M, Rohl L, Gyldensted C, Gjedde A, Østergaard L (2000) Cerebral blood flow and blood volume measured by magnetic resonance imaging bolus tracking after acute stroke in pigs: comparison with [(15)O]H(2)O positron emission tomography. Stroke 31: 1958-1964.

157. Mirz F, Gjedde A, Ishizu K, Pedersen CB (2000) Cortical networks subserving the perception of tinnitus–a PET study. Acta Otolaryngol Suppl. 543: 241-243.

158. Johannsen P, Jakobsen J, Gjedde A (2000) Statistical maps of cerebral blood flow deficits in Alzheimer’s disease. Eur J Neurol 7: 385-392.

159. Vafaee MS, Meyer E, Gjedde A (2000) Impaired activation of oxygen consumption and blood flow in visual cortex of patients with mitochondrial encephalomyopathy. Ann Neurol 48: 676-679.

160. Sakoh M, Ostergaard L, Rohl L, Smith DF, Simonsen CZ, Sorensen JC, Poulsen PV, Gyldensted C, Sakaki S, Gjedde A (2000) Relationship between residual cerebral blood flow and oxygen metabolism as predictive of ischemic tissue viability: sequential multitracer positron emission tomography scanning of middle cerebral artery occlusion during the critical first 6 hours after stroke in pigs. J Neurosurg 93: 647-657.

161. Danielsen EH, Smith D, Hermansen F, Gjedde A, Cumming P (2001) Acute neuroleptic stimulates DOPA decarboxylase in porcine brain in vivo. Synapse 41: 172-175

162. Cumming P, Danielsen EH, Vafaee M, Falborg L, Steffensen E, Sorensen JC, Gillings N, Bender D, Marthi K, Andersen F, Munk O, Smith D, Moller A, Gjedde A (2001) Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts. Acta Neurol Scand 103: 309-315

163. Smith DF, Bender D, Marthi K, Cumming P, Hansen SB, Peters D, Østergaard Nielsen E, Scheel-Krüger J, Gjedde A (2001) Synthesis and evaluation of racemic [11C]NS2456 and enantiomers as selective serotonin reuptake radiotracers for PET.  Nucl Med Biol 28: 265-270

164. Gjedde A, Wong DF (2001) Quantification of neuroreceptors in living human brain. V. Endogenous neurotransmitter inhibition of haloperidol binding in psychosis. J Cereb Blood Flow Metab 21: 982-994.

165. Smith DF, Hansen SB, Østergaard L, Gee AD, Danielsen E, Ishizu K, Bender D, Poulsen PH, Gjedde A (2001) [14C]Serotonin uptake and [O-methyl-11C]venlafaxine kinetics in porcine brain. Nucl Med Biol 28: 633-638.

166. Sakoh M, Ostergaard L, Gjedde A, Rohl L, Vestergaard-Poulsen P, Smith DF, Le Bihan D, Sakaki S, Gyldensted C (2001) Prediction of tissue survival after middle cerebral artery occlusion based on changes in the apparent diffusion of water. J Neurosurg 95: 450-458.

167. Danielsen EH, Smith DF, Andersen F, Gee AD, Bender D, Hansen SB, Hermansen F, Østergaard L, Cumming P, Gjedde A (2001) FDOPA metabolism in the adult porcine brain: influence of tracer circulation time and VOI selection on estimates of striatal DOPA decarboxylation. J Neurosci Methods 111: 157-168.

168. Videbech P, Ravnkilde B, Pedersen AR, Egander A, Landbo B, Rasmussen NA, Andersen F, Stødkilde-Jørgensen H, Gjedde A, Rosenberg R (2001) The Danish PET/depression project: PET findings in patients with major depression. Psychol Med 31: 1147-1158.

169. Watanabe H, Andersen F, Simonsen CZ, Evans SM, Gjedde A, Cumming P (2001) MR-based statistical atlas of the Gottingen minipig brain. Neuroimage 14: 1089-1096.

170. Ptito M, Kupers R, Faubert J, Gjedde A (2001) Cortical representation of inward and outward radial motion in man. Neuroimage 14: 1409-1415.

171. Witting N, Kupers RC, Svensson P, Arendt-Nielsen L, Gjedde A, Jensen TS (2001) Experimental brush-evoked allodynia activates posterior parietal cortex. Neurology 57: 1817-1824.

172. Gjedde A, Marrett S (2001) Glycolysis in neurons, not astrocytes, delays oxidative metabolism of human visual cortex during sustained checkerboard stimulation in vivo. J Cereb Blood Flow Metab 21: 1384-1392.

173. Marthi K, Bender D, Gjedde A, Smith DF (2002) [11C]Mirtazapine for PET neuroimaging: Radiosynthesis and initial evaluation in the living porcine brain. Eur Neuropsychopharmacol 12: 427-432.

174. Ravnkilde B, Videbech P, Rosenberg R, Gjedde A, Gade A (2002) Putative tests of frontal lobe function: A PET-study of brain activation during Stroop’s test and Verbal Fluency. J Clin Exp Neuropsychol 24: 534-547.

175. Videbech P, Ravnkilde B, Pedersen TH, Hartvig H, Egander A, Clemmensen K, Rasmussen NA, Andersen F, Gjedde A, Rosenberg R (2002) The Danish PET/depression project: clinical symptoms and cerebral blood flow. A regions-of-interest
analysis. Acta Psychiatr Scand 106: 35-44.

176. Cumming P, Wong DF, Gillings N, Hilton J, Scheffel U, Gjedde A(2002) Specific binding of [11C]raclopride and N-[(3)H]propyl-norapomorphine to dopamine receptors in living mouse striatum: occupancy by endogenous dopamine and guanosine triphosphate-free G protein. J Cereb Blood Flow Metab 22: 596-604.

177. Gjedde A (2002) Cerebral blood flow change in arterial hypoxemia is consistent with negligible oxygen tension in brain mitochondria. Neuroimage 17: 1876-1881.

178. Dall AM, Danielsen EH, Sørensen JC, Andersen F, Møller A, Zimmer J, Gjedde A, Cumming P (2002) Quantitative [18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned minipigs. Cell Transplant 11: 733-746.

179. Rasmussen M, Poulsen PH, Treiber A, Delahaye S, Tankisi A, Cold GE, Therkelsen K, Gjedde A, Astrup J (2003) No influence of the endothelin receptor antagonist bosentan on basal and indomethacin-induced reduction of cerebral blood flow in pigs. Acta Anaesthesiol Scand 47: 200-207.

180. Geday J, Gjedde A, Boldsen AS, Kupers R (2003) Emotional valence modulates activity in the posterior fusiform gyrus and inferior medial prefrontal cortex in social perception. Neuroimage 18: 675-684.

181. Gründer G, Vernaleken I, Muller MJ, Davids E, Heydari N, Buchholz HG, Bartenstein P, Munk OL, Stoeter P, Wong DF, Gjedde A, Cumming P (2003). Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo. Neuropsychopharmacology 28: 787-794.

182. Videbech P, Ravnkilde B, Kristensen S, Egander A, Clemmensen K, Rasmussen NA, Gjedde A, Rosenberg R (2003) The Danish PET/depression project: poor verbal fluency performance despite normal prefrontal activation in patients with major depression. Psychiatry Res 123: 49-63.

183. Ptito M, Faubert J, Gjedde A, Kupers R (2003) Separate neural pathways for contour and biological-motion cues in motion-defined animal shapes. Neuroimage 19: 246-252.

184. Fortin A, Faubert J, Ptito A, Gjedde A, Kupers R, Ptito M (2003) Stereoscopic processing in the human brain as a function of binocular luminance rivalry. Neuroreport 14: 1163-1166.

185. Cumming P, Gillings NM, Jensen SB, Bjarkam C, Gjedde A (2003) Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs. Nucl Med Biol 30: 547-553.

186. Cumming P, Rosa-Neto P, Watanabe H, Smith D, Bender D, Clarke PB, Gjedde A (2003) Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. Neuroimage 19: 1127-1136.

187. Sakoh M, Gjedde A (2003). Neuroprotection in hypothermia linked to redistribution of oxygen in brain. Am J Physiol 285: H17-H25.

188. Ravnkilde B, Videbech P, Clemmensen K, Egander A, Rasmussen NA, Gjedde A, Rosenberg R, Gade A (2003) The Danish PET/depression project: cognitive function and regional cerebral blood flow. Acta Psychiatr Scand 108: 32-40.

189. Arnfred SM, Lind NM, Moustgaard A, Hansen AK, Gjedde A (2003) Minipig negative slow wave demonstrates target/nontarget differences in P300 paradigm. Neuroimage 20: 587-590.

190. Borbely K, Gjedde A, Nyary I, Czirjak S, Donauer N, Buck A (2003) Speech activation of language dominant hemisphere: a single-photon emission computed tomography study. Neuroimage 20: 987—994.

191. Vafaee MS, Gjedde A (2004) Spatially dissociated flow-metabolism coupling in brain activation. Neuroimage 21: 507-515.

192. Vafaee MS, Østergaard K, Sunde N, Gjedde A, Dupont E, Cumming P (2004) Focal changes of oxygen consumption in cerebral cortex of patients with Parkinson’s disease during subthalamic stimulation. Neuroimage 22: 966-974.

193. Arnfred SM, Lind NM, Gjedde A, Hansen AK (2004) Scalp recordings of mid-latency AEP and auditory gating in the Gottingen minipig: a new animal model in information processing research. Int J Psychophysiol 52: 267-275.

194. Videbech P, Ravnkilde B, Gammelgaard L, Egander A, Clemmensen K, Rasmussen NA, Gjedde A, Rosenberg R (2004) The Danish PET/depression project: performance on Stroop’s test linked to white matter lesions in the brain. Psychiatry Res 130: 117-130.

195. Lou HC, Rosa P, Pryds O, Karrebaek H, Lunding J, Cumming P,Gjedde A (2004) ADHD: Increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow. Dev Med Child Neurol 46: 179-183.

196. Rosa-Neto P, Gjedde A, Olsen AK, Jensen SB, Munk OL, Watanabe H, Cumming P (2004) MDMA-evoked changes in [(11)C]raclopride and [(11)C]NMSP binding in living pig brain. Synapse 53: 222-233.

197. Rosa-Neto P, Olsen AK, Gjedde A, Watanabe H, Cumming P (2004) MDMA-evoked changes in cerebral blood flow in living porcine brain: Correlation with hyperthermia. Synapse 53: 214-221.

198. Kumakura Y, Danielsen EH, Reilhac A, Gjedde A, Cumming P (2004) Levodopa effect on [18F]fluorodopa influx to brain: normal volunteers and patients with Parkinson’s disease. Acta Neurol Scand 110: 188-195.

199. Schlünzen L, Vafaee MS, Cold GE, Rasmussen M, Nielsen JF, Gjedde A (2004) Effects of subanaesthetic and anaesthetic doses of sevoflurane on regional cerebral blood flow in healthy volunteers. A positron emission tomographic study. Acta Anaesthesiol Scand 48: 1268-1276.

200. Kupers RC, Fortin A, Astrup J, Gjedde A, Ptito M (2004) Recovery of anterograde amnesia in a case of craniopharyngioma. Arch Neurol 61: 1948-1952

201. Vuust P, Pallesen KP, Bailey C, van Zuijen TL, Gjedde A, Roepstorff A, Østergaard L (2005) To musicians, the message is in the meter. Pre-attentive neuronal responses to incongruent rhythm are left-lateralized in musicians. Neuroimage 24: 560-564.

202. Gjedde A, Johannsen P, Cold GE, Østergaard L (2005) Cerebral metabolic response to low blood flow: Possible role of cytochrome oxidase inhibition. J Cereb Blood Flow Metab 25: 1183-1196.

203. Lind NM, Olsen AK, Moustgaard A, Jensen SB, Jaboksen S, Hansen AK, Arnfred AM, Hemmingsen RP, Gjedde A, Cumming P (2005) Mapping the amphetamine-evoked dopamine release in the brain of the Gttingen minipig. Brain Res Bull 65: 1-9.

204. Ptito M, Moesgaard SM, Gjedde A, Kupers R (2005) Crossmodal plasticity revealed by electrotactile stimulation of the tongue in the congenitally blind. Brain 128: 606-614.

205. Rosa-Neto P, Lou HC, Cumming P, Pryds O, Karrebaek H, Lunding J, Gjedde A (2005) Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit. Neuroimage 25: 868-876.

206. Kumakura Y, Vernaleken I, Gr¨under G, Bartenstein P, Gjedde A, Cumming P (2005) PET studies of net blood-brain clearance of FDOPA to human brain: Age-dependent decline of [18F]fluorodopamine storage capacity. J Cereb Blood Flow Metab 25: 807-819.

207. Mortensen MV, Madsen S, Gjedde A (2005) Cortical responses to promontorial stimulation in postlingual deafness. Hear Res 209: 32-41

208. Lind NM, Gjedde A, Moustgaard A, Olsen AK, Jensen SB, Jakobsen S, Arnfred SM, Hansen AK, Hemmingsen RP, Cumming P (2005) Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs. Behav Brain Res 164: 172-177.

209. Villeneuve MY, Kupers R, Gjedde A, Ptito M, Casanova C (2005) Pattern-motion selectivity in the human pulvinar. Neuroimage 28: 474-480.

210. Mortensen MV, Madsen S, Gjedde A (2005) Use of time differences in normal hearing–cortical processing of promontorial stimuli. Hear Res 205: 94-101.

211. Jelsing J, Olsen AK, Cumming P, Gjedde A, Hansen AK, Arnfred S, Hemmingsen R, Pakkenberg B (2005) A volumetric screening procedure for the Gottingen minipig brain. Exp Brain Res 162: 428-435.

212. Pallesen KJ, Brattico E, Bailey C, Korvenoja A, Koivisto J, Gjedde A, Carlson S (2005) Emotion processing of major, minor, and dissonant chords: a functional magnetic resonance imaging study. Ann N Y Acad Sci 1060: 450-453.

213. Kumakura Y, Gjedde A, Danielsen EH, Christensen S, Cumming P (2006) Dopamine storage capacity in caudate and
putamen of patients with early Parkinson’s disease: correlation with asymmetry of motor symptoms. J Cereb Blood
Flow Metab 26: 358-370

214. Mortensen MV, Mirz F, Gjedde A (2006) Restored speech comprehension linked to activity in left inferior prefrontal and right temporal cortices in postlingual deafness. Neuroimage 31: 842-852.

215. Geday JA, Østergaard K, Gjedde A (2006) Stimulation of the subthalamic nucleus inhibits emotional activation of the fusiform gyrus. Neuroimage 33: 706-714.

216. Wong DF, Kuwabara H, Schretlen DJ, Bonson KR, Zhou Y, Nandi A, Brasic J, Kimes AS, Maris MA, Kumar A, Contoreggi C, Links J, Ernst M, Rousset O, Zukin S, Grace AA, Rohde C, Jasinski DR, Gjedde A, London ED (2006) Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology 31: 2716-2727.

217. Kupers R, Fumal A, Maertens de Noordhout A, Gjedde A, Schoenen J, Ptito M (2006) TMS of the visual cortex induces somatotopically organized qualia in blind subjects. Proc Nat Acad Sci (USA) 103: 13256-13260.

218. Rasmussen P, Dawson EA, Nybo L, van Lieshout JJ, Secher N, Gjedde A (2007) Capillary oxygenation-level-dependent (COLD) near-infrared spectrometry (NIRS) in frontal lobe of humans. J Cereb Blood Flow Metab 27: 1082-1093.

219. Johansen ML, Bak LK, Schousboe A, Iversen P, Sorensen M, Keiding S, Vilstrup H, Gjedde A, Ott P, Waagepetersen HS (2007). The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes. Neurochem Int. 50: 1042-1051.

220. Møller M, Frandsen J, Andersen G, Gjedde A, Vestergaard-Poulsen P, Østergaard L (2007). Dynamic changes in corticospinal tracts after stroke detected by fibretracking. J Neurol Neurosurg Psychiatry 78: 587-592.

221. Møller M, Jakobsen S, Gjedde A (2007). Parametric and Regional Maps of Free Serotonin 5HT(1A) Receptor Sites in Human Brain as Function of Age in Healthy Humans. Neuropsychopharmacology 32: 1707-1714.

222. Møller M, Andersen G, Gjedde A (2007). Serotonin 5HT1A receptor availability and pathological crying after stroke. Acta Neurol Scand. 116: 83-90.

223. Geday J, Kupers R, Gjedde A (2007). As Time Goes By: Temporal Constraints on Emotional Activation of Inferior Medial Prefrontal Cortex. Cereb Cortex 17: 2753-2759.

224. Hall NM, Gjedde A, Kupers R (2008) Neural mechanisms of voluntary and involuntary recall: A PET study. Behav Brain Res 186: 261-272.

225. Ptito M, Fumal A, de Noordhout AM, Schoenen J, Gjedde A, Kupers R (2008). TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers. Exp Brain Res. 184: 193-200.

226. Wong DF, Braic JR, Singer HS, Schretlen DJ, Kuwabara H, Zhou Y, Nandi A, Maris MA, Alexander M, Ye W, Rousset O, Kumar A, Szabo Z, Gjedde A, Grace AA (2008) Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: Clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology 33: 1239-1251.

227. Lerche S, Brock B, Rungby J, Bøtker HE, Møller N, Rodell A, Bibby BM, Holst JJ, Schmitz O, Gjedde A (2008) Glucagon-like-peptide-1 inhibits blood-brain glucose transfer in humans. Diabetes 57: 325-331.

228. Borghammer P, Jonsdottir KY, Cumming P, Østergaard K, Vang K, Ashkanian M, Vafaee M, Iversen P, Gjedde A (2008) Normalization in PET group comparison studies–the importance of a valid reference region. Neuroimage 40: 529-540.

229. Ashkanian M, Borghammer P, Gjedde A, Østergaard L, Vafaee M (2008) Improvement of brain tissue oxygenation by inhalation of carbogen. Neuroscience 156: 932-938.

230. Pallesen KJ, Brattico E, Bailey CJ, Korvenoja A, Gjedde A (2008) Cognitive and emotional modulation of brain default operation. J Cogn Neurosci 21: 1068-1080,

231. Rasmussen P, Overgaard A, Bjerre AF, Bjarrum M, Carlsson C, Petersen N, Nielsen HB, Volianitis S, Gjedde A, Secher NH (2010) The effects of normoxia, hypoxia, and hyperoxia on cerebral haemoglobin saturation using near infrared spectroscopy during maximal exercise. International Journal of Industrial Ergonomics, 40(2): 190-196, 2010.

Copenhagen 2008-2018

232. Ashkanian M, Gjedde A, Mouridsen K, Vafaee M, Hansen KV, Østergaard L, Andersen G (2009). Carbogen inhalation increases oxygen transport to hypoperfused brain tissue in patients with occlusive carotid artery disease: increased oxygen transport to hypoperfused brain. Brain Res. 2009 Dec 22;1304:90-5. Epub 2009 Sep 25. PubMed PMID: 19782665.

233. Bech S, Petersen T, Nørremølle A, Gjedde A, Ehlers L, Eiberg H, Hjermind LE, Hasholt L, Lundorf E, Nielsen JE (2009). Huntington’s disease-like and ataxia syndromes: Identification of a family with a de novo SCA17/TBP mutation. Parkinsonism Relat Disord. 2009 Jul 10. [Epub ahead of print] PubMed PMID: 19595623.

234. Borghammer P, Østergaard K, Cumming P, Gjedde A, Rodell A, Hall N, Mallar Chakravarty M (2010). A deformation-based morphometry study of patients with early-stage Parkinson’s disease. Eur J Neurol. 17(2): 314-320, 2010. PubMed PMID: 19912319.

235. Borghammer P, Cumming P, Aanerud J, Gjedde A (2009) Artefactual subcortical hyperperfusion in PET studies normalized to global mean: Lessons from Parkinson’s disease. Neuroimage 45: 249-257.

236. Borghammer P, Aanerud J, Gjedde A (2009) Data-driven intensity normalization of PET group comparison studies is superior to global mean normalization. Neuroimage 46(4): 981-988, 2009. doi: 10.1016/j.neuroimage.2009 .03.021. Epub Mar 19, 2009. [Epub ahead of print]

237. Borghammer P, Cumming P, Aanerud J, Förster S, Gjedde A (2009) Subcortical elevation of metabolism in Parkinson’s disease – A critical reappraisal in the context of global mean normalization. Neuroimage 47(4): 1514-1521, 2009. Epub May 22, 2009 [Epub ahead of print] PubMed PMID: 19465133.

238. Geday J, Østergaard K, Johnsen E, Gjedde A (2009) STN-stimulation in Parkinson’s disease restores striatal inhibition of thalamocortical projection. Hum Brain Mapp 30: 112-121.

239. Geday J, Gjedde A (2009) Attention, emotion, and deactivation of default activity in inferior medial prefrontal cortex. Brain Cogn 69: 344-352.

240. Geday J, Gjedde A (2009) Monoaminergic modulation of emotional impact in inferomedial prefrontal cortex. Synapse 63: 160-166.

241. Gjedde A, Geday J. (2009) Deep brain stimulation reveals emotional impact processing in ventromedial prefrontal cortex. PLoS One. 2009 Dec 7;4(12):e8120. PubMed PMID: 19997647; PubMed Central PMCID: PMC2781158.

242. Ho YC, Cheze A, Sitoh YY, Petersen ET, Goh KY, Gjedde A, Golay X. (2009) Residual neurovascular function and retinotopy in a case of hemianopia. Ann Acad Med Singapore. 2009 Sep;38(9):827-31. PubMed PMID: 19816644.

243. Iversen P, Sørensen M, Bak LK, Waagepetersen HS, Vafaee MS, Borghammer P, Mouridsen K, Jensen SB, Vilstrup H, Schousboe A, Ott P, Gjedde A, Keiding S (2009) Low cerebral oxygen consumption and blood flow in patients with cirrhosis and an acute episode of hepatic encephalopathy. Gastroenterology 136: 863-871.

244. Kumakura Y, Danielsen EH, Gjedde A, Vernaleken I, Buchholz HG, Heinz A, Grnder G, Bartenstein P, Cumming P. Elevated [(18)F]FDOPA utilization in the periaqueductal gray and medial nucleus accumbens of patients with early Parkinson’s disease. Neuroimage. 2009 Nov 24. [Epub ahead of print] PubMed PMID: 19941962.

245. Møller M, Rodell A, Gjedde A. Parametric mapping of 5HT1A receptor sites in the human brain with the Hypotime method: theory and normal values. J Nucl Med. 2009 Aug;50(8):1229-36. Epub 2009 Jul 17. PubMed PMID: 19617338.

246. Pallesen KJ, Brattico E, Bailey CJ, Korvenoja A, Gjedde A. Cognitive and emotional modulation of brain default operation. J Cogn Neurosci. 2009 Jun;21(6):1065-80. PubMed PMID: 18752396.

247. Petersen B, Mortensen MV, Gjedde A, Vuust P. Reestablishing speech understanding through musical ear training after cochlear implantation: a study of the potential cortical plasticity in the brain. Ann N Y Acad Sci. 2009Jul;1169:437-40. PubMed PMID: 19673820.

248. Ptito M, Matteau I, Gjedde A, Kupers R (2009) Recruitment of the middle temporal area by tactile motion in congenital blindness. Neuroreport 20: 543-547.

249. Rasmussen P, Madsen CA, Nielsen HB, Zaar M, Gjedde A, Secher NH, Quistorff B (2009). Coupling between the blood lactate-to-pyruvate ratio and MCA Vmean at the onset of exercise in humans. J Appl Physiol. 2009 Dec; 107(6): 1799-805. Epub 2009 Sep 24. PubMed PMID: 19779155.

250. Thomsen K, Piilgaard H, Gjedde A, Bonvento G, Lauritzen M (2009) Principal cell spiking, post-synaptic excitation and oxygen consumption in the rat cerebellar cortex. J Neurophysiol. 2009 Jul 1. [Epub ahead of print] PubMed PMID: 19571198.

251. Borghammer P, Østergaard K, Cumming P, Gjedde A, Rodell A, Hall N, Chakravarty MM. A deformation-based morphometry study of patients with early-stage Parkinson’s disease. Eur J Neurol. 2010 Feb;17(2):314-20. Epub 2009 Nov 11. PubMed PMID: 19912319.

252. Kumakura Y, Danielsen EH, Gjedde A, Vernaleken I, Buchholz HG, Heinz A, Grnder G, Bartenstein P, Cumming P. Elevated [(18)F]FDOPA utilization in the periaqueductal gray and medial nucleus accumbens of patients with early Parkinson’s disease. Neuroimage. 2010 Feb 15;49(4):2933-9. Epub 2009 Nov 24. PubMed PMID: 19941962.

253. Schl¨unzen L, Juul N, Hansen KV, Gjedde A, Cold GE. Regional cerebral glucose metabolism during sevoflurane anaesthesia in healthy subjects studied with positron emission tomography. Acta Anaesthesiol Scand. 2010 May;54(5):603-9. Epub 2010 Jan 18. PubMed PMID: 20085540.

254. Rasmussen P, Nybo L, Volianitis S, Møller K, Secher NH, Gjedde A. Cerebral oxygenation is reduced during hyperthermic exercise in humans. Acta Physiol (Oxf). 2010 May;199(1):63-70. Epub 2010 Jan 25. PubMed PMID: 20102344.

255. Gjedde A, Kumakura Y, Cumming P, Linnet J, Møller A. Inverted-U-shaped correlation between dopamine receptor availability in striatum and sensation seeking. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3870-5. Epub 2010 Feb 4. PubMed PMID: 20133675; PubMed Central PMCID: PMC2840468.

256. Gjedde A, Keiding S, Vilstrup H, Iversen P. No oxygen delivery limitation in hepatic encephalopathy. Metab Brain Dis. 2010 Mar;25(1):57-63. Epub 2010 Feb 25. PubMed PMID: 20182779.

257. Kuzminskyte R, Kupers R, Videbech P, Gjedde A, Fink P. Increased sensitivity to supra-threshold painful stimuli in patients with multiple functional somatic symptoms (MFS). Brain Res Bull. 2010 Apr 29;82(1-2):135-40. Epub 2010 Mar 17. PubMed PMID: 20223284.

258. Borghammer P, Chakravarty M, Jonsdottir KY, Sato N, Matsuda H, Ito K, Arahata Y, Kato T, Gjedde A. Cortical hypometabolism and hypoperfusion in Parkinson’s disease is extensive: probably even at early disease stages. Brain Struct Funct. 2010 May;214(4):303-17. Epub 2010 Apr 2. PubMed PMID: 20361208.

259. Rasmussen P, Nielsen J, Overgaard M, Krogh-Madsen R, Gjedde A, Secher NH, Petersen NC. Reduced muscle activation during exercise related to brain oxygenation and metabolism in humans. J Physiol. 2010 Jun 1;588(Pt 11):1985-95. Epub 2010 Apr 19. PubMed PMID: 20403976.

260. Pallesen KJ, Brattico E, Bailey CJ, Korvenoja A, Koivisto J, Gjedde A, Carlson S. Cognitive control in auditory working memory is enhanced in musicians. PLoS One. 2010 Jun 15;5(6):e11120. PubMed PMID: 20559545.

261. Linnet J, Peterson E, Doudet DJ, Gjedde A, Møller A. Dopamine release in ventral striatum of pathological gamblers losing memory. Acta Psychiatr Scand. 2010 Oct;122(4):326-33. Epub 2010 Aug 15. PubMed PMID: 20712823.

262. Peterson E, Møller A, Doudet DJ, Bailey CJ, Hansen KV, Rodell A, Linnet J, Gjedde A. Pathological gambling: relation of skin conductance response to dopaminergic neurotransmission and sensation-seeking. Eur Neuropsychoparmacol. 2010 Nov;20(11):766-75. Epub 2010 Sep 1. PubMed PMID: 20813510.

263. Borghammer P, Hansen SB, Eggers C, Chakravarty M, Vang K, Aanerud J, Hilker R, Heiss WD, Rodell A, Munk OL, Keator D, Gjedde A. Glucose metabolism in small subcortical structures in Parkinson’s disease. Acta Neurol Scand. 2012 May;125(5):303-10. doi: 10.1111/j.1600-0404.2011.01556.x. Epub 2011 Jun 21. PubMed PMID: 21692755.

264. Linnet J, Møller A, Peterson E, Gjedde A, Doudet D. Dopamine release in ventral striatum during Iowa Gambling Task performance is associated with increased excitement levels in pathological gambling. Addiction. 2011 Feb;106(2):383-90. doi: 10.1111/j.1360-0443.2010.03126.x. Epub 2010 Sep 30. PubMed PMID: 20883460.

265. Linnet J, Møller A, Petersen E, Gjedde A, Doudet D. Inverse association between dopaminergic neurotransmission and Iowa Gambling Task performance in pathological gamblers and healthy controls. Scand J Psychol. 2011 Feb;52(1):28-34. doi: 10.1111/j.1467-9450.2010.00837.x. PubMed PMID: 20704689.

266. Lundby L, Møller A, Buntzen S, Krogh K, Vang K, Gjedde A, Laurberg S. Relief of fecal incontinence by sacral nerve stimulation linked to focal brain activation. Dis Colon Rectum. 2011 Mar;54(3):318-23. PubMed PMID: 21304303.

267. Borghammer P, Cumming P, stergaard K, Gjedde A, Rodell A, Bailey CJ, Vafaee MS. Cerebral oxygen metabolism in patients with early Parkinson’s disease. J Neurol Sci. 2012 Feb 15;313(1-2):123-8. Epub 2011 Oct 4. PubMed PMID: 21975016.

268. Lauritzen F, Heuser K, de Lanerolle NC, Lee TS, Spencer DD, Kim JH,Gjedde A, Eid T, Bergersen LH. Redistribution of monocarboxylate transporter 2 on the surface of astrocytes in the human epileptogenic hippocampus. Glia. 2012 Jul;60(7):1172-81. doi: 10.1002/glia.22344. Epub 2012 Apr 25. PubMed PMID: 22535546.

269. Gejl M, Søndergaard HM, Stecher C, Bibby BM, Møller N, Bøtker HE, Hansen SB, Gjedde A, Rungby J, Brock B. Exenatide Alters Myocardial Glucose Transport and Uptake Depending on Insulin Resistance and Increases Myocardial Blood Flow in Patients with Type 2 Diabetes. J Clin Endocrinol Metab. 2012 Apr 27. [Epub ahead of print] PubMed PMID: 22544917.

270. Rodell A, Aanerud J, Braendgaard H, Gjedde A (2012) Low residual CBF variability in Alzheimer’s disease after correction for CO2 effect. Frontiers in Neuroenergetics 2012;4:8. doi: 10.3389/fnene.2012.00008. Epub 2012 Jul 5. PubMed PMID: 22783187; PubMed Central PMCID: PMC3389721.

271. Egefjord L, Gejl M, Møller A, Brændgaard H, Gottrup H, Antropova O, Møller N, Poulsen HE, Gjedde A, Brock B, Rungby J. Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimers disease – protocol for a controlled, randomized double-blinded trial. Dan Med J. 2012 Oct;59(10):A4519. PubMed PMID: 23158895.

272. Gejl M, Egefjord L, Lerche S, Vang K, Bibby BM, Holst JJ, Mengel A, Møller N, Rungby J, Brock B, Gjedde A. Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia. J Cereb Blood Flow Metab. 2012 Dec;32(12):2146-52. doi: 10.1038/jcbfm.2012.118. Epub 2012 Aug 29. PubMed PMID: 22929437; PubMed Central PMCID: PMC3519409.

273. Linnet J, Mouridsen K, Peterson E, Møller A, Doudet DJ, Gjedde A. Striatal dopamine release codes uncertainty in pathological gambling. Psychiatry Res. 2012 Oct 30;204(1):55-60. doi: 10.1016/j.pscychresns.2012.04.012. Epub 2012 Aug 11. PubMed PMID: 22889563.

274. Vafaee MS, Vang K, Bergersen LH, Gjedde A. Oxygen consumption and blood flow coupling in human motor cortex during intense finger tapping: implication for a role of lactate. J Cereb Blood Flow Metab. 2012 Oct;32(10):1859-68. doi: 10.1038/jcbfm.2012.89. Epub 2012 Jul 11. PubMed PMID: 22781333; PubMed Central PMCID: PMC3463880.

275. Nahimi A, Høltzermann M, Landau AM, Simonsen M, Jakobsen S, Alstrup AK, Vang K, Møller A,Wegener G, Gjedde A, Doudet DJ. Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning. J Neurochem. 2012 Mar;120(5):806-17. doi: 10.1111/j.1471-4159.2011.07598.x. Epub 2012 Jan 23. PubMed PMID: 22117574.

276. Bailey CJ, Sanganahalli BG, Herman P, Blumenfeld H, Gjedde A, Hyder F (2012) Analysis of Time and Space Invariance of BOLD Responses in the Rat Visual System. Cereb Cortex. 2013 Jan;23(1):210-22. doi: 10.1093/cercor/bhs008. Epub 2012 Jan 31. PubMed PMID: 22298731; PubMed Central PMCID: PMC3513959.

277. Gejl M, Lerche S, Egefjord L, Brock B, Møller N, Vang K, Rodell AB, Bibby BM, Holst JJ, Rungby J, Gjedde A. Glucagon-like peptide-1 (GLP-1) raises blood-brain glucose transfer capacity and hexokinase activity in human brain. Front Neuroenergetics. 2013;5:2. doi: 10.3389/fnene.2013.00002. Epub 2013 Mar 27. PubMed PMID: 23543638; PubMed Central PMCID: PMC3608902.

278. Fast R, Rodell A, Gjedde A, Mouridsen K, Alstrup AK, Bjarkam CR, West MJ, Berendt M, Møller A (2013). PiB Fails to Map Amyloid Deposits in Cerebral Cortex of Aged Dogs with Canine Cognitive Dysfunction. Front Aging Neurosci. 2013 Dec 30;5:99. doi: 10.3389/fnagi.2013.00099. PubMed PMID: 24416017; PubMed Central PMCID: PMC3874561.

279. Petersen B, Gjedde A, Wallentin M, Vuust P. Cortical plasticity after cochlear implantation. Neural Plast. 2013;2013: 318521. doi: 10.1155/2013/318521. Epub 2013 Nov 26. PubMed PMID: 24377050; PubMed Central PMCID: PMC3860139.

280. Rodell A, Aanerud J, Brændgaard H, Gjedde A. Washout allometric reference method (WARM) for parametric analysis of [(11)C]PIB in human brains. Front Aging Neurosci. 2013 Nov 27;5:45. doi: 10.3389/fnagi.2013.00045. PubMed PMID: 24348416; PubMed Central PMCID: PMC3842163.

281. Darusman HS, Call J, Sajuthi D, Schapiro SJ, Gjedde A, Kalliokoski O, Hau J. Delayed response task performance as a function of age in cynomolgus monkeys (Macaca fascicularis). Primates. 2013 Nov 19. [Epub ahead of print] PubMed PMID: 24248474.

282. Gjedde A, Aanerud J, Brændgaard H, Rodell AB. Blood-brain transfer of Pittsburgh compound B in humans. Front Aging Neurosci. 2013 Nov 7;5:70. doi: 10.3389/fnagi.2013.00070. PubMed PMID: 24223554; PubMed Central PMCID: PMC3819578.

283. Alstrup AK, Landau AM, Holden JE, Jakobsen S, Schacht AC, Audrain H, Wegener G, Hansen AK, Gjedde A, Doudet DJ. Effects of anesthesia and species on the uptake or binding of radioligands in vivo in the Göttingen minipig. Biomed Res Int. 2013;2013:808713. doi: 10.1155/2013/808713. Epub 2013 Sep 8. PubMed PMID: 24083242; PubMed Central PMCID: PMC3780537.

284. Kumakura Y, Gjedde A, Caprioli D, Kienast T, Beck A, Plotkin M, Schlagenhauf F, Vernaleken I, Gründer G, Bartenstein
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285. Rodell A, Rasmussen LJ, Bergersen LH, Singh KK, Gjedde A. Natural selection of mitochondria during somatic lifetime promotes healthy aging. Front Neuroenergetics. 2013 Aug 12;5:7. doi: 10.3389/fnene.2013.00007. eCollection 2013. PubMed PMID: 23964235; PubMed Central PMCID: PMC3740293.

286. Ioannides AA, Liu L, Poghosyan V, Saridis GA, Gjedde A, Ptito M, Kupers R. MEG reveals a fast pathway from somatosensory cortex to occipital areas via posterior parietal cortex in a blind subject. Front Hum Neurosci. 2013 Aug 5;7:429. doi: 10.3389/fnhum.2013.00429. eCollection 2013. PubMed PMID: 23935576; PubMed Central PMCID: PMC3733019.

287. Callesen MB, Hansen KV, Gjedde A, Linnet J, Møller A. Dopaminergic and clinical correlates of pathological gambling in Parkinson’s disease: a case report. Front Behav Neurosci. 2013 Jul 29;7:95. doi: 10.3389/fnbeh.2013.00095. eCollection 2013. PubMed PMID: 23908610; PubMed Central PMCID: PMC3725950.

288. Lauritzen KH, Morland C, Puchades M, Holm-Hansen S, Hagelin EM, Lauritzen F, Attramadal H, Storm-Mathisen J, Gjedde A, Bergersen LH. Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism. Cereb Cortex. 2013 May 21. [Epub ahead of print] PubMed PMID: 23696276.

289. Medin T, Rinholm JE, Owe SG, Sagvolden T, Gjedde A, Storm-Mathisen J, Bergersen LH. Low dopamine D5 receptor density in hippocampus in an animal model of attention-deficit/hyperactivity disorder (ADHD). Neuroscience. 2013 Jul 9;242:11-20. doi: 10.1016/j.neuroscience.2013.03.036. Epub 2013 Mar 27. PubMed PMID: 23541742.

290. Darusman HS, Sajuthi D, Kalliokoski O, Jacobsen KR, Call J, Schapiro SJ, Gjedde A, Abelson KS, Hau J. Correlations between serum levels of beta amyloid, cerebrospinal levels of tau and phospho tau, and delayed response tasks in young and aged cynomolgus monkeys (Macaca fascicularis). J Med Primatol. 2013 Jun;42(3):137-46. doi: 10.1111/jmp.12044. Epub 2013 Mar 26. PubMed PMID: 23530983.

291. Gejl M, Lerche S, Mengel A, Møller N, Bibby BM, Smidt K, Brock B, Søndergaard H, Bøtker HE, Gjedde A, Holst JJ, Hansen SB, Rungby J. Influence of GLP-1 on Myocardial Glucose Metabolism in Healthy Men during Normo- or Hypoglycemia. PLoS One. 2014 Jan 6;9(1):e83758. doi: 10.1371/journal.pone.0083758. PubMed PMID: 24400077; PubMed Central PMCID: PMC3882300.

292. Darusman HS, Pandelaki J, Mulyadi R, Sajuthi D, Putri IA, Kalliokoski OH, Call J, Abelson KS, Schapiro SJ, Gjedde A, Hau J. Poor memory performance in aged cynomolgus monkeys with hippocampal atrophy, depletion of amyloid Beta 1-42 and accumulation of tau proteins in cerebrospinal fluid. In Vivo. 2014 Mar-Apr;28(2):173-84. PubMed PMID: 24632970.

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294. Gejl M, Rungby J, Brock B, Gjedde A. At the Centennial of Michaelis and Menten, Competing Michaelis-Menten Steps Explain Effect of GLP-1 on Blood-Brain Transfer and Metabolism of Glucose. Basic Clin Pharmacol Toxicol. 2014 Mar 29. doi: 10.1111/bcpt.12240. [Epub ahead of print] PubMed PMID: 24684709.

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297. Iversen P, Mouridsen K, Hansen MB, Jensen SB, Sørensen M, Bak LK, Waagepetersen HS, Schousboe A, Ott P, Vilstrup H, Keiding S, Gjedde A. Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [(11)C]acetate in humans. Front Neurosci. 2014 Nov 3;8:353. doi: 10.3389/fnins.2014.00353. eCollection 2014. PubMed PMID: 25404890; PubMed Central PMCID: PMC4217371.

298. Darusman HS, Kalliokoski O, Sajuthi D, Schapiro SJ, Gjedde A, Hau J. The success rate in a complicated spatial memory test is determined by age, sex, life history and search strategies in cynomolgus monkeys. In Vivo. 2014 Sep-Oct;28(5):741-50. PubMed PMID: 25189885.

299. Hansen J, Brock B, Bøtker HE, Gjedde A, Rungby J, Gejl M (2014) Impact of glucagon-like peptide-1 on myocardial glucose metabolism revisited. Rev Endocr Metab Disord. 2014 Sep;15(3):219-31. doi: 10.1007/s11154-014-9286-8. PubMed PMID: 24910203.

300. Stender J, Kupers R, Rodell A, Thibaut A, Chatelle C, Bruno MA, Gejl M, Bernard C, Hustinx R, Laureys S, Gjedde A. Quantitative rates of brain metabolism distinguish minimally conscious from vegetative state patients. J Cereb Blood Flow Metab. 2015 Jan;35(1):58-65. doi: 10.1038/jcbfm.2014.169. Epub 2014 Oct 8. PubMed PMID: 25294128; PubMed Central PMCID: PMC4294395.

301. Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IR, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH. Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease. Neurochem Res. 2015 Dec 16. [Epub ahead of print] PubMed PMID: 26677077.

302. Arnold A, Calvetti D, Gjedde A, Iversen P, Somersalo E. Astrocytic tracer dynamics estimated from [1-11C]-acetate PET measurements. Math Med Biol. 2015 Dec;32(4):367-82. doi: 10.1093/imammb/dqu021. Epub 2014 Nov 24. PubMed PMID: 25424579.

303. Andalib S, Talebi M, Sakhinia E, Farhoudi M, Sadeghi-Bazargani H, Gjedde A. Lack of association between mitochondrial DNA G15257A and G15812A variations and multiple sclerosis. J Neurol Sci. 2015 Sep 15;356(1-2):102-6. doi: 10.1016/j.jns.2015.06.022. Epub 2015 Jun 12. PubMed PMID: 26233806.

304. Andalib S, Talebi M, Sakhinia E, Farhoudi M, Sadeghi-Bazargani H, Gjedde A. Mitochondrial DNA T4216C and A4917G variations in multiple sclerosis. J Neurol Sci. 2015 Sep 15;356(1-2):55-60. doi: 10.1016/j.jns.2015.04.050. Epub 2015 May 7. PubMed PMID: 26201854.

305. Landau AM, Dyve S, Jakobsen S, Alstrup AK, Gjedde A, Doudet DJ. Acute Vagal Nerve Stimulation Lowers alpha2 Adrenoceptor Availability: Possible Mechanism of Therapeutic Action. Brain Stimul. 2015 Jul-Aug;8(4):702-7. doi: 10.1016/j.brs.2015.02.003. Epub 2015 Feb 13. PubMed PMID: 25758422.

306. Vafaee MS, Gjedde A, Imamirad N, Vang K, Chakravarty MM, Lerch JP, Cumming P. Smoking normalizes cerebral blood flow and oxygen consumption after 12-hour abstention. J Cereb Blood Flow Metab. 2015 Mar 31;35(4):699-705. doi: 10.1038/jcbfm.2014.246. PubMed PMID: 25605288; PubMed Central PMCID: PMC4420887.

307. Phan JA, Landau AM, Wong DF, Jakobsen S, Nahimi A, Doudet DJ, Gjedde A. Quantification of [(11)C]yohimbine binding to a2 adrenoceptors in rat brain in vivo. J Cereb Blood FlowMetab. 2015 Mar;35(3):501-11. doi: 10.1038/jcbfm. 2014.225. Epub 2015 Jan 7. PubMed PMID: 25564241; PubMed Central PMCID: PMC4348393.

308. Nahimi A, Jakobsen S, Munk OL, Vang K, Phan JA, Rodell A, Gjedde A. Mapping a2 adrenoceptors of the human brain with 11C-yohimbine. J Nucl Med. 2015 Mar;56(3):392-8. doi: 10.2967/jnumed.114.145565. Epub 2015 Jan 29. PubMed PMID: 25635132.

309. Verbeken M, Wynendaele E, Mauchauffe E, Bracke N, Stalmans S, Bojnik E, Benyhe S, Peremans K, Polis I, Burvenich C, Gjedde A, Hernandez JF, De Spiegeleer B. Blood-brain transfer and antinociception of linear and cyclic N-methylguanidine and thiourea-enkephalins. Peptides. 2015 Jan;63:10-21. doi: 10.1016/j.peptides.2014.10.010. Epub 2014 Nov 4. PubMed PMID: 25451468.

310. Pallesen KJ, Bailey CJ, Brattico E, Gjedde A, Palva JM, Palva S. Experience Drives Synchronization: The phase and Amplitude Dynamics of Neural Oscillations to Musical Chords Are DifferentiallyModulated by Musical Expertise. PLoS One. 2015 Aug 20;10(8):e0134211. doi: 10.1371/journal.pone.0134211. eCollection 2015. PubMed PMID: 26291324; PubMed Central PMCID: PMC4546391.

311. Hyder F, Herman P, Bailey CJ, Møller A, Globinsky R, Fulbright RK, Rothman DL, Gjedde A. Uniform distributions of glucose oxidation and oxygen extraction in gray matter of normal human brain: No evidence of regional differences of aerobic glycolysis. J Cereb Blood Flow Metab. 2016 May;36(5):903-16. doi: 10.1177/0271678X15625349. PubMed PMID: 26755443; PubMed Central PMCID: PMC4853838.

312. Holm-Hansen S, Low JK, Zieba J, Gjedde A, Bergersen LH, Karl T (2016). Behavioural effects of high fat diet in a mutant mouse model for the schizophrenia risk gene neuregulin 1. Genes Brain Behav. 2016 Mar;15(3):295-304. doi: 10.1111/gbb.12267. PubMed PMID: 26707035.

313. Stender J, Mortensen KN, Thibaut A, Darkner S, Laureys S, Gjedde A, Kupers R (2016). The minimal energetic requirement of sustained awareness after brain injury. Current Biology 2016 6(11): 1494-1499. doi: 10.1016/j.cub.2016.04.024. Epub 2016 May 26.

314. Gejl M, Gjedde A, Egefjord L, Mller A, Hansen SB, Vang K, Rodell A, Brndgaard H, Gottrup H, Schacht A, Møller N, Brock B, Rungby J. In Alzheimer’s Disease, 6-Month Treatment with GLP-1 Analog Prevents Decline of Brain Glucose Metabolism: Randomized, Placebo-Controlled, Double-Blind Clinical Trial. Front Aging Neurosci. 2016 May 24;8:108. doi: 10.3389/fnagi.2016.00108. PubMed PMID: 27252647; PubMed Central PMCID: PMC4877513.

315. Gjedde A, Marrett S (2016). In Search of Baseline: Absolute and Relative Blood Flow and Oxidative Metabolism in Visual Cortex Stimulated at Three Levels of Complexity. Journal of Experimental and Clinical Neurosciences (JECNS). Published September 23, 2016. doi: 10:13183/JECNS.V311.42 Corpus ID. 54753943.

316. Lauritzen KH, Hasan-Olive MM, Regnell CE, Kleppa L, Scheibye-Knudsen M, Gjedde A, Klungland A, Bohr VA, Storm-Mathisen J, Bergersen LH. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016 Dec;48:34-47. doi: 10.1016/j.neurobiolaging.2016.08.005. PubMed PMID: 27639119.

317. Aanerud J, Borghammer P, Rodell A, Jónsdottir KY, Gjedde A (2016). Sex differences of human cortical blood flow and energy metabolism. J Cereb Blood Flow Metab. 2016 Jan 1:271678X16668536. doi: 10.1177/0271678X16668536. [Epub ahead of print] PubMed PMID: 27629099.

318. Segtnan EA, Grupe P, Jarden JO, Gerke O, Ivanidze J, Christlieb SB, Constantinescu C, Pedersen JE, Houshmand S, Hess S, Zarei M, Gjedde A, Alavi A, Høilund-Carlsen PF. Prognostic implications of total hemispheric glucose metabolism ratio in cerebro-cerebellar diaschisis. J Nucl Med. 2016 Oct 27. pii: jnumed.116.180398. [Epub ahead of print] PubMed PMID: 27789719.

319. Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IR, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH. Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease. Neurochem Res. 2016 Jun;41(6):1229-36. doi: 10.1007/s11064-015-1792-x. Review. Erratum in: Neurochem Res. 2016 Jun;41(6):1237. PubMed PMID: 26677077.

320. Rodell AB, O’Keefe G, Rowe CC, Villemagne VL, Gjedde A. Cerebral Blood Flow and A-Amyloid Estimates by WARM Analysis of [(11)C]PiB Uptake Distinguish among and between Neurodegenerative Disorders and Aging. Front Aging Neurosci. 2017 Jan 11;8:321. doi: 10.3389/fnagi.2016.00321. PubMed PMID: 28123366; PubMed Central PMCID: PMC5225115.

321. Andalib S, Sakhinia E, Talebi M, Farhoudi M, Sadeghi-Bazargani H, Masoodian N, Balaghi-Inaloo M, Vafaee MS, Gjedde A (2017). No evidence of association between optic neuritis and secondary LHON mtDNA mutations in patients withmultiple sclerosis. Mitochondrion 36: 182-185, 2017. doi: 10.1016/j.mito.2017.08.005. Epub 2017 Aug 10.

322. Adjmal Nahimi,1,2 Karen Østergaard,3 Malene F. Damholdt6, Jenny Ann Phan,1 Michael Wintherdahl,1 Tatyana Fedorova, 1 Steen Jakobsen,1 Dirk Bender,1 Anders Rodell,1,2 Ole L. Munk,1 Per Borghammer,1 and Gjedde A2,4,5. alpha-2-Adrenoceptors in motor function and cognition in Parkinsons disease. In press in J Nucl Med.

323. Phan JA, Stokholm K, Zareba-Paslawska J, Jakobsen S, Vang K, Gjedde A, Landau AM, Romero-Ramos M (2017). Early synaptic dysfunction induced by a-synuclein in a rat model of Parkinson’s disease. Sci Rep. 2017 Jul 25;7(1):6363. doi: 10.1038/s41598-017-06724-9. PubMed PMID: 28743955; PubMed Central PMCID: PMC5526979.

324. Gejl M, Brock B, Egefjord L, Vang K, Rungby J, Gjedde A (2017). Blood-Brain Glucose Transfer in Alzheimer’s disease: Effect of GLP-1 Analog Treatment. Sci Rep. 2017 Dec 13;7(1):17490. doi: 10.1038/s41598-017-17718-y. PubMed PMID: 29235507; PubMed Central PMCID: PMC5727512.

325. Mortensen K, Gjedde A, Garth Thompson, Peter Herman, Maxime Parent, Douglas L. Rothman, Ron Kupers, Maurice Ptito, Johan Stender, Steven Laureys, Valentin Riedl, Michael T. Alkire, and Fahmeed Hyder (2018) Impact of global mean normalization on regional glucose metabolism in the human brain. Neural Plasticity 2018 Jun 12; 2018:6120925. doi: 10.1155/2018/6120925. eCollection 2018.

326. Landau AM, Alstrup AK, Audrain H, Jakobsen S, Simonsen M, Møller A, Videbech P, Wegener G, Gjedde A, Doudet DJ (2018). Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. J Cereb Blood Flow Metab. 2018 May;38(5):881-887. doi: 10.1177/0271678X17705260. Epub 2017 May 16. PubMed PMID: 28509598; PubMed Central PMCID: PMC5987930.

327. Nahimi A, Sommerauer M, Kinnerup MB, stergaard K, Winterdahl M, Jacobsen J, Schacht A, Johnsen B, Damholdt MF, Borghammer P, Gjedde A (2018) Noradrenergic Deficits in Parkinson Disease Imaged with (11)C-MeNER. J Nucl Med. 2018 Apr;59(4):659-664. doi: 10.2967/jnumed.117.190975. Epub 2017 Aug 28. Erratum in: J Nucl Med. 2018 Sep;59(9):1473. PubMed PMID: 28848039.

328. Gejl M, Gjedde A, Brock B, Mller A, van Duinkerken E, Haahr HL, Hansen CT, Chu PL, Stender-Petersen KL, Rungby J (2018). Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial. Diabetologia. 2018 Mar;61(3):551-561. doi: 10.1007/s00125-017-4502-1. Epub 2017 Nov 29. PubMed PMID: 29188338.

329. Wong DF, Kuwabara H, Horti AG, Roberts JM, Nandi A, Cascella N, Brasic J, Weerts EM, Kitzmiller K, Phan JA, Gapasin L, Sawa A, Valentine H, Wand G, Mishra C, George N, McDonald M, Lesniak W, Holt DP, Azad BB, Dannals RF, Kem W, Freedman R, Gjedde A (2018). Brain PET Imaging of a7-nAChR with [18F]ASEM: Reproducibility, Occupancy, Receptor Density, and Changes in Schizophrenia. Int J Neuropsychopharmacol. 2018 Jul 1;21(7):656-667. doi: 10.1093/ijnp/pyy021. PubMed PMID: 29522184; PubMed Central PMCID: PMC6030963.

330. Phan JA, Landau AM, Jakobsen S, Wong DF, Gjedde A (2018). Radioligand binding analysis of alpha(2) adrenoceptors with [(11)C]yohimbine in brain in vivo: Extended Inhibition Plot correction for plasma protein binding. Sci Rep. 2018 Apr 16;8(1):6249. doi: 10.1038/s41598-018-24170-z. PubMed PMID: 29662067; PubMed Central PMCID: PMC5902620.

331. Wong DF, Blue ME, Braic JR, Nandi A, Valentine H, Stansfield KH, Rousset O, Bibat G, Yablonski ME, Johnston MV, Gjedde A, Naidu S (2018). Are dopamine receptor and transporter changes in Rett syndrome reflected in Mecp2-deficient mice? Exp Neurol. 2018 Sep;307:74-81. doi: 10.1016/j.expneurol.2018.05.019. Epub 2018 May 18. PubMed PMID: 29782864.

332. Mortensen KN, Gjedde A, Thompson GJ, Herman P, Parent MJ, Rothman DL, Kupers R, Ptito M, Stender J, Laureys S, Riedl V, Alkire MT, Hyder F (2018). Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain. Neural Plast. 2018 Jun 12;2018:6120925. doi: 10.1155/2018/6120925. eCollection 2018. PubMed PMID: 30008742; PubMed Central PMCID: PMC6020504.

333. Majdi A, Sadigh-Eteghad S, Talebi M, Farajdokht F, Erfani M, Mahmoudi J, Gjedde A (2018). Nicotine Modulates Cognitive Function in D-Galactose-Induced Senescence inMice. Front Aging Neurosci. 2018 Jul 13;10:194. doi: 10.3389/fnagi.2018. 00194. eCollection 2018. PubMed PMID: 30061821; PubMed Central PMCID: PMC6055060.

334. Benveniste H, Dienel G, Jacob Z, Lee H, Makaryus R, Gjedde A, Hyder F, Rothman DL (2018). Trajectories of Brain Lactate and Re-visited Oxygen-Glucose Index Calculations Do Not Support Elevated Non-oxidative Metabolism of Glucose Across Childhood. Front Neurosci. 2018 Sep 11;12:631. doi: 10.3389/fnins.2018.00631. eCollection 2018. PubMed PMID: 30254563; PubMed Central PMCID: PMC6141825

Odense 2019-2020

335. Olsen BB, Gjedde A, Vilstrup MH, Johnsen IBG, Neumann G, Torigian DA, Alavi A, Høilund-Carlsen PF (2019). Linked Hexokinase and Glucose-6-Phosphatase Activities Reflect Grade of Ovarian Malignancy. Mol Imaging Biol. Apr; 21(2): 375-381. doi: 10.1007/s11307-018-1247-2. PubMed PMID: 29987620.

336. Andalib S, Talebi M, Sakhinia E, Farhoudi M, Sadeghi-Bazargani H, Masoudian N, Michel TM, Vafaee MS, Gjedde A (2019). Mitochondrial DNA G15927A and G15928A variations in patients with multiple sclerosis. Mult Scler Relat Disord. 2019 Jan;27:9-12. doi: 10.1016/j.msard.2018.09.004. Epub 2018 Sep 7. PubMed PMID: 30292021.

337. Segtnan, E.A., Majdi, A., Constantinescu, C., Grupe P., Gerke O., Dali, H., Strøm O.E., Holm J., Alavi A., Sadigh-Eteghad S., Wermuth L., Hildebrandt MG., Gjedde A. Høilund-Carlsen PF (2019) Diagnostic manifestations of total hemispheric glucose metabolism ratio in neuronal network diaschisis: diagnostic implications in Alzheimer’s disease and mild cognitive impairment. Eur J Nucl Med Mol Imaging 2019 Jan 12. https://doi.org/10.1007/s00259-018-4248-0

338. Salehpour F, Farajdokht F, Mahmoudi J, Erfani M, Farhoudi M, Karimi P, Rasta SH, Sadigh-Eteghad S, Hamblin MR, Gjedde A (2019). Photobiomodulation and Coenzyme Q(10) Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. Front Cell Neurosci. 2019 Mar 19;13:74. doi: 10.3389/fncel.2019.00074. eCollection 2019. PubMed PMID: 30983970; PubMed Central PMCID: PMC6434313.

339. Landau AM, Alstrup AKO, Noer O, Winterdahl M, Audrain H, Møller A, Videbech P, Wegener G, Gjedde A, Doudet DJ (2019).  Electroconvulsive stimulation differentially affects [(11)C]MDL100,907 binding to cortical and subcortical 5HT(2A) receptors in porcine brain. J Psychopharmacol. 2019 Mar 19:269881119836212. doi: 10.1177/0269881119836212. [Epub ahead of print] PubMed PMID: 30887871.

340. Mortensen KN, Sanggaard S, Mestre H, Lee H, Kostrikov S, Xavier ALR, Gjedde A, Benveniste H, Nedergaard M (2019) Impaired Glymphatic Transport in Spontaneously Hypertensive Rats. J Neurosci in press

341. Jeeun Kang, Haichong K. Zhang, Shilpa D. Kadam, Fedorko Julie, Heather Valentine, Jin U. Kang, Arman Rahmim, Gjedde A, Leslie M. Loew, Dean F. Wong, Emad M. Boctor (2019) Transcranial real-time in vivo recording of electrophysiological neural activity in the rodent brain with near-infrared photoacoustic voltage-sensitive dye imaging. Frontiers in Neuroscience in press.

342. Michael Winterdahl, Ove Noer, Dariusz Orlowski, Anna C. Schacht, Steen Jakobsen, Aage K.O. Alstrup, Gjedde A, Anne M. Landau (2019) Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain. Sci Rep in press.

343. Landau AM, Noer O, Alstrup AKO, Audrain H, Wegener G, Gjedde A, Doudet DJ, Winterdahl M (2020). Type of Anaesthetic Influences [(11)C]MDL100,907 Binding to 5HT(2A) Receptors in Porcine Brain. Mol Imaging Biol. 2020 Jan 28. doi: 10.1007/s11307-020-01476-x. [Epub ahead of print] PubMed PMID: 31993926.

344. Kang J, Kadam SD, Elmore JS, Sullivan BJ, Valentine H, Malla AP, Harraz MM, Rahmim A, Kang JU, Loew LM, Baumann MH, Grace AA, Gjedde A, Boctor EM, Wong DF (2020). Transcranial photoacoustic imaging of NMDA evoked focal circuit dynamics in the rat hippocampus. J Neural Eng. 2020 Apr 8;17(2):025001. doi: 10.1088/1741-2552/ab78ca. PubMed PMID: 32084654; PubMed Central PMCID: PMC7145727.

345. Justinussen J, Dall C, Dencker D, Gjedde A, Fink-Jensen A, Thomsen M (2020). Revealing a compulsive phenotype in cholinergic M(4)(-/-) mice depends on the inter-trial interval initiation settings in a five choice serial reaction time task. Behav Brain Res. 2020 Apr 25:112649. doi: 10.1016/j.bbr.2020.112649. [Epub ahead of print] PubMed PMID: 32344038.

Copenhagen/Aarhus 2021-

346. Bornebusch AB, Mason GF, Tonetto S, Damsgaard J, Gjedde A, Fink-Jensen A, Thomsen M (2021). Effects of ketogenic diet and ketone monoester supplement on acute alcohol withdrawal symptoms in male mice. Psychopharmacology (Berl). 2021 Mar;238(3):833-844. doi: 10.1007/s00213-020-05735-1. Epub 2021 Jan 7. PMID: 33410985; PMCID: PMC7914216.

347. Faber J, E. Eldrup, C. Selmer, C. Pichat, S. Hecquet, T.Watt, S. Kreimer, B. Karpatschof, F. Gyntelberg, S. Ballegaard, Gjedde A (2021). Reduction of pressure pain sensitivity as novel non-pharmacological therapeutic approach to type 2 diabetes: A randomized trial. Frontiers in Neuroscience. Revised version9 20210120

348. Henriksen OM, Gjedde A, Kim Vang, Ian Law, Joel Aanerud, Egill Rostrup (2021). Regional and interindividual relationships between cerebral perfusion and oxygen metabolism. Journal of Applied Physiology.

349. Alireza Majdi, Saeed Sadigh-Eteghad, Gjedde A (2021) Effects of Transdermal Nicotine Delivery on Cognitive Outcomes in Healthy Adults: A Meta-Analysis. Accepted in Acta Neurologica Scandinavica.

350. Sigvard AK, Nielsen MØ, Gjedde A, Bojesen KB, Fuglø D, Tangmose K, Kumakura Y, Heltø K, Ebdrup BH, Jensen LT, Rostrup E, Glenthøj BY (2021). Dopaminergic Activity in Antipsychotic-Nave Patients Assessed With Positron Emission Tomography Before and After Partial Dopamine D2 Receptor Agonist Treatment: Association With Psychotic Symptoms and Treatment Response. Biol Psychiatry. 2022 Jan 15;91(2):236-245. doi: 10.1016/j.biopsych.2021.08.023. Epub 2021 Sep 10. Erratum in: Biol Psychiatry. 2022 Jul 15;92(2):170. PMID: 34743917.

351. Sigvard AK, Bojesen KB, Ambrosen KS, Nielsen MØ, Gjedde A, Tangmose K, Kumakura Y, Edden R, Dan Fuglø, Jensen LT, Rostrup E, Ebdrup BH, Glenthøj BY (2022). Dopamine Synthesis Capacity and GABA and Glutamate Levels Separate Antipsychotic-Nave Patients With First-Episode Psychosis From Healthy Control Subjects in a Multimodal Prediction Model, Biological Psychiatry Global Open Science, 2022, ISSN 2667-1743, https://doi.org/10.1016/j.bpsgos.2022.05.004.

352. Khodaii J, Araj-Khodaei M, Vafaee MS, Wong DF, Gjedde A(2022). Relative Strengths of Three Linearizations of Receptor Availability: Saturation, Inhibition, and Occupancy Plots. J Nucl Med. 2022 Feb;63(2):294-301. doi: 10.2967/jnumed.117.204453. Epub 2021 Jun 4. PMID: 34088774; PMCID: PMC8805780.

353. Chang NHS, Kumakura Y, Møller A, Linnet J, Bender D, Doudet DJ, Vafaee MS, Gjedde A (2022). On the learning of addictive behavior: Sensation-seeking propensity predicts dopamine turnover in dorsal striatum. Brain Imaging Behav. 2022 Feb;16(1):355-365. doi: 10.1007/s11682-021-00509-5. Epub 2021 Aug 21. PMID: 34417966; PMCID: PMC8825434.

354. Vestergaard MB, Ghanizada H, Lindberg U, Arngrim N, Paulson OB, Gjedde A, Ashina M, Larsson HBW (2022). Human Cerebral Perfusion, Oxygen Consumption, and Lactate Production in Response to Hypoxic Exposure. Cereb Cortex. 2022 Mar 4;32(6):1295-1306. doi: 10.1093/cercor/bhab294. PMID: 34448827; PMCID: PMC8924433.

355. Rischel EB, Gejl M, Brock B, Rungby J, Gjedde A (2022). In Alzheimer’s disease, amyloid beta accumulation is a protective mechanism that ultimately fails. Alzheimers Dement. 2022 Jun 8. doi: 10.1002/alz.12701. Epub ahead of print. PMID: 35673950.

356. Khodaii J, Nomura Y, Chang NHS, Wong DF, Møller A, Gjedde A (2022). Dopamine D2/3 Receptor Availabilities in Striatal and Extrastriatal Regions of the Adult Human Brain: Comparison of Four Methods of Analysis. Neurochem Res. 2022 Dec 16. doi: 10.1007/s11064-022-03825-4. Epub ahead of print. PMID: 36525123.

357. Phan JA, Wong DF, Chang NHS, Kumakura Y, Bauer WR, Gjedde A (2022). Transient equilibrium determination of dopamine D2/D3 receptor densities and affinities in brain. Front. Nucl. Med., 01 December 2022 Sec. PET and SPECT ttps://doi.org/10.3389/fnume.2022.1030387

358. Oka N, Sakoh M, Hirayama M, Niiyama M, Gjedde A (2023) Asymmetry of signal intensities of corticofugal tracts in T2-weighted brain images reflects manual dexterity. Accepted by Scientific Reports.

359. Rossi R, Brentzen SL, Thomsen MB, Real CC, Wegener G, Grassi-Oliveira R, Gjedde A, Landau AM (2023) A single dose of cocaine increases SV2A density in hippocampus of adolescent rats. Accepted.

360. Faber J, Ballegaard S, Ørsted N, Eldrup E, Karpatschof B, Gyntelberg F, Hecquet SK, Gjedde A (2023) In Type 2 Diabetes Mellitus, normalization of hemoglobin A1c accompanies reduced sensitivity to painful pressure at the sternum. Submitted to Frontiers in Neuroscience, received on 11 Oct 2022

Original Papers in Preparation

361. Kemp AF, Nahimi A, Kinnerup M, Gjedde A (2023). EEG and 2-receptor availability in brain of patients with Parkinson’s disease. In preparation

362. Filip L H Fredensborg, Kasper Thilsing-Hansen, Jane A Simonsen, Peter Grupe, Ziba A Farahani, Christian W Andersen, Albert Gjedde, Svend Hvidsten. Dynamic multi-pinhole collimated brain SPECT of Parkinson’s disease by [123I]FP-CIT: A feasibility study of fSPECT. In preparation

363. Gjedde A (2023). Aerobic Glycolysis in Brain: The fate of phosphorylated glucose molecules that are not oxidized in cerebral cortex. In preparation

Editorials, Perspectives, Protocols, and Reviews

364. Gjedde A (1983) Modulation of substrate transport to the brain. Acta Neurol Scand 67: 3-25.

365. Gjedde A, Crone C (1983) Biochemical modulation of blood-brain barrier permeability. Acta Neuropathol (Berl) Suppl VIII: 59-74.

366. Gjedde A (1986) The selective barrrier between blood and brain. Trends in Biochemical Sciences 11: 525-527.

367. Gjedde A (1987) Does deoxyglucose uptake in the brain reflect energy metabolism? Biochem Pharmacol 36: 1853-1862.

368. Gjedde A, Bodsch W (1987) Facilitated diffusion across the blood-brain barrier: Interactions between receptors and transporters. Wissenschaftl Zeitschr Karl Marx Univ (Leipzig) 36: 67-71.

369. Gjedde A, Wong DF (1987) Positron tomographic quantitation of neuroreceptors in human brain in vivo – with special reference to the D2 dopamine receptors in caudate nucleus. Neurosurg Rev 10: 9-17.

370. Andreasen N, Carson R, Diksic M, Evans A, Farde L, Gjedde A, Hakim A, Lal S, Nair N, Sedvall G, Tune L, Wong DF (1988) Schizophrenia, positron tomography, and dopamine D2 receptors in the human neostriatum. Schizophr Bull 14: 471-484.

371. Gjedde A (1988) Positron tomography, schizophrenia, and dopamine in the living human brain. Hospimedica 6: 19-27.

372. Gjedde A (1989) Positron tomograms of the human brain recovering from stroke. Hospimedica 7: 17-25.

373. Redies C, Gjedde A (1989) Double-label and conventional deoxyglucose methods: a practical guide for the user. Cerebrovasc Brain Metab Rev 1: 319-367.

374. Gjedde A (1992) Labeled carbon dioxide: How transient a metabolite? J Nucl Med 32: 585-586.

375. Kuwabara H, Ohta S, Brust P, Meyer E, Gjedde A (1992) Density of perfused capillaries in living human brain during functional activation. Prog Brain Res 91: 209-215.

376. Wong DF, Gjedde A (1996) Compartments and reaction volumes of brain fluid spaces: Shaken, not stirred. J Nucl Med 37: 126-127.

377. Zatorre RJ, Meyer E, Gjedde A, Evans AC (1996) PET studies of phonetic processing of speech – review, replication, and reanalysis. Cerebral Cortex 6: 21-30.

378. Bøtker HE, Bøttcher M, Gjedde A, Nielsen TT (1998) [Positron emission tomography of the heart. From research to clinical practice]. Positron emissions tomografi af hjertet. Fra forskning til klinisk praksis. Nord Med 113: 78-81

379. Gjedde A (1999) Gradients of the brain. Brain 122: 2013-2014.

380. Keiding S; Schiøtt KM; Vilstrup H; Gjedde A (1999) Positron-emissionstomografi af levertumorer. Ugeskr Laeger 161: 6163-6165

381. Gjedde A (2001) [Receptor mapping in living human beings by means of positron emission tomography] Ugeskr Laeger 163: 5199-5205.

382. Gjedde A, Marrett S, Vafaee M (2002) Oxidative and nonoxidative metabolism of excited neurons and astrocytes. J Cereb Blood Flow Metab 22: 1-14.

383. Gjedde A (2003) Imaging bones of contention. Acta Orthop Scand 74: 631–632.

384. Hyder F, Patel AB, Gjedde A, Rothman DL, Behar KL, Shulman RG (2006) Neuronal-glial glucose oxidation and glutamatergic-GABAergic function. J Cereb Blood Flow Metab 26: 865-877.

385. Innis RB, Cunningham VJ, Delforge J, Fujita M, Gjedde A, Gunn RN, Holden J, Houle S, Huang SC, Ichise M, Iida H, Ito H, Kimura Y, Koeppe RA, Knudsen GM, Knuuti J, Lammertsma AA, Laruelle M, Logan J, Maguire RP, Mintun MA, Morris ED, Parsey R, Price JC, Slifstein M, Sossi V, Suhara T, Votaw JR, Wong DF, Carson RE (2007) Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab. 27: 1533-1539.

386. Gjedde A (2008) Functional brain imaging celebrates 30th anniversary. Acta Neurol Scand. 117: 219-223.

387. Falkai P, Mike O, Inez MG, Paul H, Andras BG, Sophia F, MEOS Consortium (Gjedde A) (2008) A roadmap to disentangle the molecular etiology of schizophrenia. Eur Psychiatry 23: 224-232.

388. Aanerud J, Borghammer P, Chakravarty MM, Vang K, Rodell AB, Jnsdottir KY, Møller A, Ashkanian M, Vafaee MS, Iversen P, Johannsen P, Gjedde A (2012) Brain Energy Metabolism and Blood Flow Differences in Healthy Aging. J Cereb Blood Flow Metab 2012 Jul;32(7):1177-87. doi: 10.1038/jcbfm.2012.18. Epub 2012 Feb 29. PubMed PMID: 22373642; PubMed Central PMCID: PMC3390816.

389. Bergersen LH, Gjedde A. Is lactate a volume transmitter of metabolic states of the brain? Front Neuroenergetics.2012;4:5. Epub 2012 Mar 19. PubMed PMID: 22457647; PubMed Central PMCID: PMC3307048.

390. Rodell A, Rasmussen LJ, Bergersen LH, Singh KK, Gjedde A. Natural selection of mitochondria during somatic lifetime promotes healthy aging. Front Neuroenergetics. 2013 Aug 12;5:7. doi: 10.3389/fnene.2013.00007. PubMed PMID: 23964235; PubMed Central PMCID: PMC3740293.

391. Stankowska AUM, Gjedde A. Perspective: Food addiction, caloric restriction, and dopaminergic neurotransmission. Acta Neuropsychiatr. 2013;:1. DOI: http://dx.doi.org/10.1017/neu.2013.18

392. Mariga ST, Kolko M, Gjedde A, Bergersen LH (2014) Lactate transport and receptor actions in cerebral malaria. Frontiers in Neuroenergetics 6 (2). doi: 10.3389/fnins.2014.00125

393. Andalib S, Vafaee MS, Gjedde A. Parkinson’s disease and mitochondrial gene variations: a review. J Neurol Sci. 2014 Nov 15;346(1-2):11-9. doi: 10.1016/j.jns.2014.07.067. Epub 2014 Aug 7. PubMed PMID: 25151610.

394. Stender J, Kupers R, Maurice Ptito M, Gjedde A (2014) Unresponsive, but Aware: The Non-Behavioral Minimally Conscious State. Brain Disord Ther 3: e115. doi:10.4172/2168-975X.1000e115

395. Morland C, Lauritzen KH, Puchades M, Holm-Hansen S, Andersson K, Gjedde A, Attramadal H, Storm-Mathisen J, Bergersen LH (2015) The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain. J Neurosci Res. 2015 Jul;93(7):1045-55. doi: 10.1002/jnr.23593. Epub 2015 Apr 16. Review. PubMed PMID: 25881750.

396. J. Stender, A. Gjedde, S. Laureys (2015) Detection of Consciousness in the Severely Injured Brain. Annual Update in Intensive Care and Emergency Medicine. Chapter: Annual Update in Intensive Care and Emergency Medicine. Volume 2015, pp 495-506

397. Andalib S, Divani AA, Michel TM, Høilund-Carlsen PF, Vafaee MS, Gjedde A (2017) Pandora’s Box of mitochondrial defects in ischemic heart disease and stroke: a review. Expert Reviews in Molecular Medicine. 2017 Apr 5;19:e5 doi: 10.1017/em.2017.5

398. Andalib S, Talebi M, Sakhinia E, Farhoudi M, Sadeghi-Bazargani H, Emamhadi M, Masoodian N, Balaghi-Inalou M, Vafaee MS, Gjedde A. (2017) Mitochondrial DNA G13708A variation in multiple sclerosis: Is there an association? Revue Neurologique. In press.

399. Mirjam Münch, Adam E. Brøndsted, Steven A. Brown, Albert Gjedde, Thomas Kantermann, Klaus Martiny, Danielle Mersch , Debra J. Skene, and Anna Wirz-Justice (2017) The effect of light on humans. Chapter 3 in Changing perspectives on daylight: Science, technology, and culture. (Science/AAAS, Washington, DC, 2017), p. 16-23.

400. Mariëlle P. J. Aarts , Steven A. Brown, Bruno Bueno, Albert Gjedde, Danielle Mersch, Mirjam Münch, Jean-Louis Scartezzini , Carlo Volf, Jan Wienold, Anna Wirz-Justice, Magali Bodart, and Jrme Kaempf (2017) Reinventing daylight. Chapter 5 in Changing perspectives on daylight: Science, technology, and culture. (Science/AAAS, Washington, DC, 2017), p. 33-37.

401. Nilsson M, Gjedde A , Brock B, Gejl M, Rungby J. (2018) The effects of incretin hormones on cerebral glucose metabolism in health and disease. Neuropharmacology 136(Pt B):243-250. doi:10.1016/j.neuropharm.2017.12.031. PubMed PMID: 29274367.

402. Høilund-Carlsen PF, Barrio JR, Gjedde A , Werner TJ, Alavi A. (2018) J Alzheimers Dis. 2018 Feb 28. doi: 10.3233/JAD-180050. [Epub ahead of print] PMID: 29504544 [PubMed – as supplied by publisher]

403. Nahimi A, Kinnerup MB, Sommerauer M, Gjedde A, Borghammer P. (2018) Molecular Imaging of the Noradrenergic System in Idiopathic Parkinson’s Disease. Int Rev Neurobiol. 2018;141:251-274. doi: 10.1016/bs.irn.2018.07.028. Epub 2018 Aug 24. PubMed PMID: 30314598.

404. Madsen SS, Gjedde A, Brandt L, Pihl-Thingvad J, Videbech P, Gerke O, Hjlund-Carlsen PF (2018). Neurobiological effects of work-related stress: protocol for a case-control neuroimaging study. Dan Med J. 2018. Nov;65(11). pii: A5513. PubMed PMID: 30382017.

405. Majdi A, Kamari F, Sadigh-Eteghad S and Gjedde A (2019) Molecular Insights Into Memory-Enhancing Metabolites of Nicotine in Brain: A Systematic Review. Front. Neurosci. 12:1002. doi: 10.3389/fnins.2018.01002

406. Rossi R, Arjmand S, Brentzen SL, Gjedde A, Landau AM (2022). Synaptic Vesicle Glycoprotein 2A: Features and Functions. Front Neurosci. 2022 Apr 28;16:864514. doi: 10.3389/fnins.2022.864514. PMID: 35573314; PMCID: PMC9096842.

407. Gjedde A, Wong DF (2022). Four decades of mapping and quantifying neuroreceptors at work in vivo by positron emission tomography. Front Neurosci. 2022 Sep 8;16:943512. doi: 10.3389/fnins.2022.943512. PMID: 36161158; PMCID: PMC9493011.

Textbooks and Textbook Chapters

408. Plum F, Gjedde A, Samson F (1976) (eds.) Neuroanatomical functional mapping by the radioactive 2-deoxy-D-glucose method. Neurosciences Research Program Bulletin, Boston.

409. Hakim A, Gjedde A (1987) (eds.) Brain87: Proceedings of the Thirteenth International Symposium on Cerebral Blood Flow and Metabolism. New York: Lippincott-Raven.

410. Lassen NA, Gjedde A (1983) Kinetic analysis of the uptake of glucose and some of its analogs in the brain, using the single capillary model: Comments on some points of controversy. In: Lecture Notes in Biomathematics 48, Tracer Kinetics and Physiologic Modeling (eds. Lambrecht RM, Rescigno A) Springer Verlag, New York, pp. 387—410.

411. Gjedde A, Wong DF (1990) Modeling neuroreceptor binding of radioligands in vivo. Quantitative Imaging of Neuroreceptors (Frost J, Wagner HNJr, eds.), Raven Press, New York, pp 51-79.

412. Gjedde A (1992) Blood-brain glucose transfer. In: Physiology and Pharmacology of the Blood-Brain Barrier, Chapter 6a: Handbook of Experimental Pharmacology, MWB Bradbury, ed. Springer-Verlag, Berlin Heidelberg 1992, pp. 65—115.

413. Gjedde A (1995) Glucose metabolism. In: Principles of Nuclear Medicine, 2nd edition, eds Wagner HNJr, Szabo Z, Buchanan JW. Saunders, Philadelphia, pp. 54—71.

414. Gjedde A (1995) Compartmental analysis. In: Principles of Nuclear Medicine, 2nd edition, eds Wagner HNJr, Szabo Z, Buchanan JW. Saunders, Philadelphia, pp. 451—461.

415. Gjedde A (1996) The relation between brain function and cerebral blood flow and metabolism. Chapter 2, In: Cerebrovascular Disease (ed Batjer HH). Lippincott-Raven, Philadelphia, pp. 23—40.

416. Gjedde A, Hansen SB, Knudsen GM, Paulson OB (2000) (eds.) Physiological Imaging of the Brain with PET. San Diego: Academic Press.

417. Gjedde A (2001) Brain energy metabolism and the physiological basis of the hemodynamic response. In: Functional Magnetic Resonance Imaging: Methods for Neuroscience. Jezzard P, Matthews PM, Smith S, (eds.) Oxford University Press, Oxford, pp. 37—65.

418. Gjedde A (2003) Modelling metabolite and tracer kinetics. In: L. E. Feinendegen, W. W. Shreeve, W. C. Eckelman, Y.-W. Bahk & H. N. Wagner Jr. (Eds), Molecular Nuclear Medicine. Springer-Verlag, Berlin, Heidelberg. Chapter 7, pp. 121–169.

419. Gjedde A (2005) Subjectivity and self: The neurobiology of consciousness. In In Search of a Language for the Mind-Brain, Bohn OS, Gjedde A, Saleemi A, eds. Cambridge: Cambridge University Press.

420. Saleemi A, Bohn OS, Gjedde A (2005) In Search of a Language for the Mind-Brain. Aarhus: Aarhus University Press.

421. Gjedde A (2006) Blood-brain transfer and metabolism of oxygen. In: Blood-Brain Barriers: From Ontogeny to Artificial Interfaces, Dermietzel RS, Spray DC, Nedergaard M, eds. Hoboken: John Wiley & Sons, Ltd., volume 2, chapter 22, pp. 523-549.

422. Gjedde A (2007) Coupling of brain function to metabolism: Evaluation of energy requirements. In Handbook of Neurochemistry: Brain energetics from genes to metabolites to cells: Integration of molecular and cellular processes. Editor-in-chief: Lajtha, Abel, Gibson, Gary; Dienel, Gerry (Eds.), 3rd ed., 400 p., 40 illus., Hardcover. ISBN: 0-387-30366-9.

423. Wong DF, Gjedde A (2009) Monoamines: Human Brain Imaging. In: Squire LR (ed.) Encyclopedia of Neuroscience, volume 5, pp. 939-952. Oxford: Academic Press.

424. Gjedde A, Bauer WR, Wong DF (2010) Neurokinetics: The Dynamics of Neurobiology in Vivo. Springer: New York 2010, pp.343.

425. Gjedde A, Magistretti P (2011) Cellular mechanisms of brain energy metabolism, 70 pp. In: Youmans Neurological Surgery, 6th Edition, ed. Winn R.

426. Gjedde A, Wong DF (2012) Molecular neuroscience and the quantification of brain dynamics. In Neuromethods. New York: Springer Science+Business Media

427. Gjedde A (2014) Positron emission tomography of brain glucose metabolism with [18F]fluorodeoxyglucose in humans.In Hirrlinger J, Waagepetersen H (eds.) Neuromethods, volume 90, pp. 341-364. New York: Humana Press

428. Dean F. Wong, Ganesh B. Chand, Gerhard Gründer, Jimmy E. Jakobsson, Gjedde A (2022) Molecular Brain Imaging in Schizophrenia. Sadock and Kaplan Textbook of Psychiatry, 2022

Review Chapters in Books

429. Wong DF, Gjedde A, Tune LE, Pearlson G, Villemagne V, Links J, Dannals RF, Wagner HN Jr (1989) Quantification of neuroreceptors in living human brain: Implications for schizophrenia research. In: Schizophhrenia: Scientific Progress (Schultz SC, Tamminga PA, eds). Oxford University Press, London, pp. 274-284.

430. Gjedde A (1990) Tracer studies of neuroreceptor kinetics in vivo. In: Positron Emission Tomography in Movement Disorders (Martin WRW, ed.), CRC Press, Boca Raton.

431. Gjedde A, Kuwabara H (1991) Kinetic analysis of glucose tracer uptake and metabolism by brain in vivo. In: Radiopharmaceuticals and Brain Pathology Studied with PET and SPECT. Diksic M and Reba RC, eds, CRC Press, Boca Raton, pp. 135-164.

432. Gjedde A (1991) Kinetic analysis of radioligand binding in brain in vivo. In: Radiopharmaceuticals and Brain Pathology Studied with PET and SPECT. Diksic M and Reba RC, eds, CRC Press, Boca Raton, pp. 337-355.

433. Pappius H, Dyve S, McHugh M, Gjedde A (1992) Effect of injury on 1-adrenoreceptors in rat brain in vivo. In: Role of Neurotransmitters in Brain Injury, (Dietrich WD, Globus MYT, eds.), Plenum Press, pp. 125-130.

434. Wong DF, Ricaurte G,  Gründer G, Rothman R, Naidu S, Singer H, Harris J, Yokoi F, Villemagne V, Szymanski S, Gjedde A, Kuhar M. (1998) Dopamine transporter changes in neuropsychiatric disorders. Adv Pharmacol 42: 219-223.

435. Gjedde A (2002) Coupling of blood flow to neuronal excitability. In: The Neuronal Environment: Brain Homeostasis in Health and Disease. Ed. Walz W, Humana Press Inc., Totowa, N.J., pp. 233-257.

436. Gjedde A (2002) Coupling and compartmentation of cerebral blood flow and metabolism. In: Cerebral Blood Flow. Mechanisms of Ischemia, Diagnosis and Therapy. Ed. Pinsky M, Springer-Verlag, Berlin-Heidelberg, pp. 72-95.

437. Gjedde A (2003) The pathway for oxygen in brain. APMIS Suppl. (109): 146-153.

438. Gjedde A, Wong DF, Rosa-Neto P, Cumming P (2005) Mapping neuroreceptors at work: On the definition and interpretation of binding potentials after 20 years of progress. Int Rev Neurobiol 63: 1—20.

439. Gjedde A (2005) The pathways of oxygen in brain I: Delivery and metabolism of oxygen. In Oxygen Transport to Tissue XXVI, Okunief P, Williams J, Chen Y eds. Adv Exp Med Biol 566: 269—275.

440. Gjedde A (2005) The pathways of oxygen in brain II: Competitions for cytochrome c oxidase and NOS are keys to flow-metabolism coupling. In Oxygen Transport to Tissue XXVI, Okunief P, Williams J, Chen Y eds. Adv Exp Med Biol 566: 277—283.

441. Stender J, Gjedde A, Laureys S (2015) Detection of Consciousness in the Severely Injured Brain. Annual Update in Intensive Care and Emergency Medicine 2015, pp 495-506.

Letters and Comments

1. Gjedde A, Schaefer JA (1975) [Brain edema and diabetic ketoacidosis] Ugeskr Læger 137: 1259—1261.

2. Gjedde A (1981) More on the meaning of ”blood-brain barrier”. Clin Chem 27: 1474.

3. Gjedde A (1982) On ”lumped constant” nomograms. J Neurochem 39: 1774-1776.

4. Gjedde A, Wong DF (1987) Neuroreceptor assay with positron emission tomography: definition of transfer coefficients. J Cereb Blood Flow Metab 7: 517-520.

5. Gjedde A, Reith J, Wong DF (1995) Dopamine receptors in schizophrenia. Lancet 346: 1302-1303.

6. Gjedde A (1995) Origins of the Patlak plot. Nucl Med Comm 16: 979-980.

7. Gjedde A, Reith J, Wong DF (1996) In schizophrenia, some dopamine D-2-like receptors are still elevated. Psychiat Res: Neuroimag 67: 159-161.

8. Gjedde A (1996) DOPA decarboxylase. Mov Disord 11: 462-463.

9. Gjedde A, Wong DF (1997) Reaction volume concept – reply. J Nucl Med 38:341-342

10. Gjedde A (1997) Dark origins of the Patlak-Gjedde-Blasberg-Fenstermacher-Rutland-Rehling plot. Nucl Med Comm 18: 274-275

11. Hermansen F. Poulsen PH. Danielsen E. Smith DF. Gee AD. Hansen SB. Gjedde A (1997) Parametric imaging of irreversible binding of C-11-NMSP requires weighted patlak analysis (vol 5, pg a30, 1997). Neuroimage 6: 230

12. Cumming P, Gjedde A, Reith J (1997) Controversies arising from recent fdopa articles. J Nucl Med 38: 1267-1269

13. Cumming P, Hermansen F, Gjedde A (1999) Cerebral dopamine concentrations during levodopa treatment. Neurology 53: 1374-1375

14. Gjedde A (2002) Metabolism of neurons and glia. Nature Reviews Neuroscience doi: 10.1038/nrn730-c1. Published online 29 November 2002.

15. Cumming P, Reith J, Gjedde A (2002) Cocaine withdrawal and the cerebral influx of [18F]fluoro-L-DOPA (FDOPA). Neuropsychopharma-cology 20: 395-396.

16. Schlünzen L, Vafaee SM, Gold GE, Rasmussen M, Nielsen JF, Gjedde A (2006) ’Different concentrations’ are more  than one. Acta Anaesthesiol Scand 50: 123-124.

History of Medicine and Obituaries

17. Gjedde A (1989) The emancipation of Miss Menten. J Cereb Blood Flow Metab 9: 243-246.

18. Basset G, Bassingthwaighte JB, Chinard FP, Gjedde A, Goresky CA, Hansen AJ (1991) An appreciation: Christian Crone (1926-1990). Microvasc Res 41: 1-4.

19. Gjedde A (1992) The Bohr effect is properly ascribed to Bohr. News Physiol Sci 7: 284-286.

20. Gjedde A (1993) In memoriam: Christian Crone (1926-1990) J Cereb Blood Flow Metab 13: 3-4.

21. Friberg L, Gjedde A (1997) In memoriam – Lassen, Niels A. – 7 December 1926 30 April 1997. Eur J Nucl Med 24: 1083-1084

22. Gjedde A (2010) Diffusive insights: on the disagreement of Christian Bohr and August Krogh at the Centennial of the Seven Little Devils. Adv Physiol Educ 34: 174-185. With permission, originally published in Danish as Gjedde A (2004) Christian Bohr and the Seven Little Devils. Dansk Medicinsk-Historisk rbog, 32: 13-40.

23. Taheri-Targhi S, Gjedde A, Araj-Khodaei M, Rikhtegar R, Parsian Z, Zarrintan S, Torbati M, Vafaee MS. (2019) Avicenna (980-1037 CE) and his Early Description and Classification of Dementia. J Alzheimers Dis. 2019;71(4):1093-1098. doi: 10.3233/JAD-190345. PMID: 31524162.